• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Study on physical and mental fatigue using biomarkers in urine and brain.

Research Project

Project/Area Number 22500614
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionDaito Bunka University

Principal Investigator

OSHIRO Satoru  大東文化大学, スポーツ・健康科学部, 教授 (30160485)

Co-Investigator(Kenkyū-buntansha) YANASE Sumino  大東文化大学, スポーツ・健康科学部, 准教授 (90249061)
TAKAYAMA Shigenobu  大東文化大学, スポーツ・健康科学部, 教授 (50407657)
MORIOKA Masaki  東京大学, 医学部附属病院, 特任助教 (30351589)
Research Collaborator IWASAWA Yuya  大東文化大学, スポーツ・健康科学研究科, 大学院生
SUGASAWA Takehito  大東文化大学, スポーツ・健康科学研究科, 大学院生
NISHIYAMA Nobuo  大東文化大学, スポーツ・健康科学研究科, 大学院生
UEDA Yasuhisa  大東文化大学, スポーツ・健康科学研究科, 大学院生
REN Jing  大東文化大学, スポーツ・健康科学研究科, 大学院生
SHIBUYA Takumi  大東文化大学, スポーツ・健康科学研究科, 大学院生
YOSHIKOSHI Chinatsu  大東文化大学, スポーツ・健康科学研究科, 大学院生
SUGA Naohiro  大東文化大学, スポーツ・健康科学研究科, 大学院生
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywordsスポーツ生化学 / 肉体疲労 / 精神疲労 / 疲労マーカー / 活性酸素 / 過酸化水素 / 疲労 / c-fos / RNA-seq / 神経科学 / DNA酸化物質8-OHdG / 概日リズム / 神経化学
Research Abstract

It is said that approximately two thirds of working population in Japan may be tired of working. The study of fatigue makes a contribution to the quality of life of the people. In this study, to investigate the difference between physical and mental fatigue, and the degree of both fatigue, we examined these biomarkers. The analysis of urine from physical or mental stress-loaded experimental animals, rats suggests that hydrogen peroxide, a reactive oxygen species is at least a kind of biomarker for physical fatigue. We will also analyze marker proteins and gene expressions related to fatigue using RNA-seq of mRNA from rat brain.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (12 results)

All 2013 2012 2011 2010

All Journal Article (2 results) Presentation (10 results) (of which Invited: 1 results)

  • [Journal Article] Relation between Physical and Mental Fatigue in Urine Biomarker, Hydrogen Peroxide2011

    • Author(s)
      Oshiro, S. Morioka M.S., Iwasawa,Y.,Ueda.Y.,Ren,J.,Yanase, S., Takayama, N
    • Journal Title

      J Neurochem(Supple.)

      Volume: 118 Pages: 239-240

    • Related Report
      2012 Final Research Report
  • [Journal Article] Relation between physical and mental fatigue in urine biomarker, hydrogen peroxide2011

    • Author(s)
      Oshiro, S., Morioka, M.S., Iwasawa, Y., Ueda, Y., Ren, J., Yanase, S., Takayama, S.
    • Journal Title

      Journal of Neurochemistry

      Volume: 118 Pages: 239-240

    • Related Report
      2011 Annual Research Report
  • [Presentation] Gene expressions related to physical and mental fatigue2013

    • Author(s)
      Oshiro, S.et al.
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] Studies on biomarkers for physical and mental fatigues2013

    • Author(s)
      Sugasawa, T., Iwasawa, Y., Nishiyama,N., Morioka, M.S.,Takayama, S.,Yanase, S and Oshiro, S.
    • Organizer
      第86回日本生化学会(発表予定)
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Annual Research Report
  • [Presentation] Icing suppresses tissue damages and oxidative stress in a rat fracture rat model.2012

    • Author(s)
      Sugasawa, T., Tanba,Taiko., Yuya Iwasawa, Sibuya, T., Hayakawa, K. and Oshiro,T.
    • Organizer
      第21回日本柔道整復接骨医学会学術大会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Measurement of biomarkers for physical and mental fatigue in animal model2011

    • Author(s)
      Iwasawa, Y., Yanase, S., Takayama, S., Morioka, M.S., Oshiro, S.
    • Organizer
      The 54^<th> annual meeting of Japanese Society for Neurochemistry第54回日本神経化学会
    • Place of Presentation
      石川県山代温泉瑠璃光
    • Year and Date
      2011-09-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Measurement of Biomarkers for Physical and Mental Fatigue in Animal Model2011

    • Author(s)
      Iwasawa, Y. Oshiro,S.Yanase,S .Takayama,S.Morioka.K
    • Organizer
      第54回日本神経化学会
    • Place of Presentation
      山代温泉(石川県)
    • Year and Date
      2011-09-26
    • Related Report
      2012 Final Research Report
  • [Presentation] Relation between physical and mental fatigue in urine biomarker, hydrogen peroxide2011

    • Author(s)
      Oshiro, S., Morioka, M.S., Iwasawa, Y., Ueda, Y., Ren, J., Yanase, S., Takayama, S.
    • Organizer
      The 23^<rd> Biennial meeting of international and European Society of Neurochemistry
    • Place of Presentation
      Athens, Greece
    • Year and Date
      2011-08-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] Relation between Physical and Mental Fatigue in Urine Biomarker, Hydrogen Peroxide2011

    • Author(s)
      Oshiro, S. et al
    • Organizer
      The 22nd Biennial Meeting of the International of Society for Nurochemistry(ISN) /Asia -Pacific Society for Neurochemistry (APSN) of Joint Meeting
    • Place of Presentation
      アテネ(ギリシャ)
    • Related Report
      2012 Final Research Report
  • [Presentation] 尿中活性酸素の日内変動2010

    • Author(s)
      吉越千夏、須賀直博、上田耕久、任 静、岩沢勇也、漆原綾香、下川美奈、米川駿、玉置潤、吉田亜希子、中島昌哉、蕪木智子、小林新、大城 聰
    • Organizer
      第33回日本分子生物学会年回・第83回日本生化学大会合同学会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-07
    • Related Report
      2012 Final Research Report
  • [Presentation] 尿中および脳内疲労マーカーを用いた肉体疲労および精神疲労の評価」2010

    • Author(s)
      大城 聰、 森岡勝樹、 高山成伸、 簗瀬澄乃
    • Organizer
      日本神経化学会・日本神経科学会合同学会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県)
    • Year and Date
      2010-09-04
    • Related Report
      2012 Final Research Report
  • [Presentation] 尿中および脳内疲労マーカーを用いた肉体疲労および精神疲労の評価2010

    • Author(s)
      大城聰、森岡勝樹、高山成伸、簗瀬澄乃
    • Organizer
      日本神経化学会・日本神経科学会合同学会
    • Place of Presentation
      神戸コンベンションセンター
    • Year and Date
      2010-09-04
    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi