Relationships between lumber disc degeneration and genetic factors in athletes
| Project/Area Number |
22500615
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Nippon Sport Science University |
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Principal Investigator |
HIRANUMA Kenji 日本体育大学, 大学院・体育科学研究科, 教授 (30434153)
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| Co-Investigator(Kenkyū-buntansha) |
小山 浩司 東京有明医療大学, 保健医療学部, 講師 (70563469)
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| Co-Investigator(Renkei-kenkyūsha) |
中里 浩一 日本体育大学, 体育学部, 教授 (00307993)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | スポーツ障害 / 椎間板変性 / 遺伝子 / 身体特性 / スポーツ / TGFbeta / CILP / アスポリン / 遺伝子多型 |
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| Research Abstract |
In this study, we surveyed susceptible gene polymorphism for lumber disc degeneration (LDD). We also examined relationship between low back pain (LBP) and radiological abnormalities in lumber region. As a result, we found that COL11A1 gene polymorphism is susceptible for limbus vertebra (LV) in collegiate gymnasts. We also found the possibilities that LV eventually induce LDD. Furthermore, we found that significant association exists between LV and LBP in gymnasts. We finally developed a novel model for LBP occurrence concomitant with genetic polymorphism and radiological abnormalities.
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Report
(4 results)
Research Products
(14 results)
