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A Study on the Toxicity of a Smokeless Tobacco, Gum Tobacco

Research Project

Project/Area Number 22500645
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionAzabu University

Principal Investigator

ENDO Osamu  麻布大学, 生命・環境科学部, 准教授 (10194028)

Co-Investigator(Renkei-kenkyūsha) GOTO Sumio  麻布大学, 生命・環境科学部, 教授 (30112890)
MORIGUCHI Toru  麻布大学, 生命・環境科学部, 教授 (10512006)
TAKAGI Yukihiko  麻布大学, 獣医学部, 教授 (30163182)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords喫煙 / 薬物乱用防止教育 / 有害化学物質 / たばこ
Research Abstract

A study on the toxicity of smokeless tobacco, such as gum tobacco which had been recently sold in Japan, was demonstrated. Some reactive products of tobacco manufactures such as tobacco leaves and gum tobacco with nitrite showed the mutagenicity for Salmonella strains. It was suggested that there were mutagens and/or carcinogens in the reactive products of gum tobacco as well as chewing tobacco which had been associated with oral cancer.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (12 results)

All 2013 2012 2011 2010

All Journal Article (2 results) (of which Peer Reviewed: 1 results) Presentation (10 results)

  • [Journal Article] Smoking topography and biomarkers of exposure among Japanese smokers: associations with cigarette emissions from machine smoking protocols2013

    • Author(s)
      Matsumoto M, Inaba Y, Yamaguchi I, Endo O, Hammond D, Uchiyama S, Suzuki G
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: 18 Issue: 2 Pages: 95-103

    • DOI

      10.1007/s12199-012-0293-7

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] たばこ煙中の成分測定2010

    • Author(s)
      後藤純雄、遠藤治、内山茂久、稲葉洋平
    • Journal Title

      臨床化学

      Volume: 39 Pages: 123-129

    • NAID

      10026446249

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] チューイングガムの亜硝酸反応生成物の変異原性2013

    • Author(s)
      遠藤治,諏訪由希子,三ッ木毬恵,後藤純雄.
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] チューイングガムの亜硝酸反応生成物の変異原性2013

    • Author(s)
      (遠藤治), 諏訪由希子, 三ッ木毬恵, 後藤純雄
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜市パシフィコ横浜
    • Related Report
      2012 Annual Research Report
  • [Presentation] 喫煙者の尿中変異原の固相抽出手法の比較(II)2012

    • Author(s)
      鈴木洵、高橋稚愛、後藤純雄、稲葉洋平、遠藤治
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Related Report
      2012 Final Research Report
  • [Presentation] ガムたばこの変異原性2012

    • Author(s)
      宇田一成、三ッ木毬恵、高木敬彦、後藤純雄、遠藤治
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Related Report
      2012 Final Research Report
  • [Presentation] ガムたばこの変異原性2012

    • Author(s)
      宇田一成、遠藤治, ほか
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 喫煙者の尿中変異原の固相抽出手法の比較(II)2012

    • Author(s)
      鈴木洵, 遠藤治, ほか
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] たばこ煙の有害性:化学物質の観点から2011

    • Author(s)
      遠藤治.
    • Organizer
      第2回日本小児禁煙研究会学術集会
    • Place of Presentation
      静岡
    • Year and Date
      2011-12-11
    • Related Report
      2012 Final Research Report
  • [Presentation] たばこ煙の有害性:化学物質の観点から2011

    • Author(s)
      遠藤治
    • Organizer
      第2回日本小児禁煙研究会学術集会
    • Place of Presentation
      静岡市(招待講演)
    • Year and Date
      2011-12-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] 喫煙者の尿中変異原の固相抽出手法の比較2011

    • Author(s)
      高橋稚愛、瀬尾卓磨、後藤純雄、稲葉洋平、遠藤治
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-30
    • Related Report
      2012 Final Research Report
  • [Presentation] 喫煙者の尿中変異原の固相抽出手法の比較2011

    • Author(s)
      高橋稚愛、遠藤治, ほか
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      ツインメツセ静岡
    • Year and Date
      2011-03-30
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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