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Effects of exercise on muscle strength and blood flow in elderly

Research Project

Project/Area Number 22500662
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionKyoto University

Principal Investigator

ISHIHARA Akihiko  京都大学, 大学院・人間・環境学研究科, 教授 (90184548)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords高齢者 / 筋力 / 血流 / 運動 / 歩行速度 / 筋持久力 / 歩行 / 運動プログラム / 走運動 / 血流量 / 有酸素運動 / 運動強度
Research Abstract

Maximal muscle strength and blood flow of the femur in elderly were measured. Thereafter, they were divided into 2 groups: the low- or high-speed walking group and continued 30-min walking for 4 weeks. There was a correlation between muscle endurance strength and blood flow, irrespective of the age. The high-speed walking group showed greater increase in both muscle endurance strength and blood flow than the low-speed walking group. The older subjects showed greater decrease in muscle endurance strength and blood flow, whereas those in the high-speed walking group showed greater improvement in muscle endurance strength and blood flow. It is concluded that the muscle endurance strength and blood flow are improved by high-speed walking, irrespective of the age.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (21 results)

All 2012 2011 2010

All Journal Article (16 results) (of which Peer Reviewed: 16 results) Presentation (5 results) (of which Invited: 2 results)

  • [Journal Article] A threshold dose of heavy ion radiation that decreases the oxidative enzyme activity of spinal motoneurons in rats2012

    • Author(s)
      Ishihara A, Nagatomo F, Fujino H, Kondo H, Nojima K
    • Journal Title

      Neurochemical Research

      Volume: 37 Pages: 387-393

    • NAID

      120003892136

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differences in capillary architecture, hemodynamics, and angiogenic factors in rat slow and fast plantarflexor muscle2012

    • Author(s)
      Fujino H, Kondo H, Murakami S, Nagatomo F, Fujita N, Takeda I, Ishihara A, Roy RR
    • Journal Title

      Muscle & Nerve

      Volume: 45 Pages: 242-249

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] High-fat diet-induced reduction of PGC-1αmRNA levels and oxidative capacity in the soleus muscle of rats with metabolic syndrome2012

    • Author(s)
      Nagatomo F, Fujino H, Kondo H, Takeda I, Tsuda K, Ishihara A
    • Journal Title

      Nutrition Research

      Volume: 32 Pages: 144-151

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of running exercise on oxidative capacity and PGC-1αmRNA levels in the soleus muscle of rats with metabolic syndrome2012

    • Author(s)
      Nagatomo F, Fujino H, Kondo H, Kouzaki K, Gu N, Takeda I, Tsuda K, Ishihara A
    • Journal Title

      Journal of Physiological Sciences

      Volume: 62 Pages: 105-114

    • NAID

      10030351596

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Lifestyle-related disease and skeletal muscle2012

    • Author(s)
      Ishihara A, Nagatomo F, Fujino H, Kondo H, Tsuda K
    • Journal Title

      Journal of Physical Fitness and Sports Medicine

      Volume: 1 Pages: 17-27

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of hyperbaric oxygen on metabolic capacity of the skeletal muscle in type 2 diabetic rats with obesity2012

    • Author(s)
      Fujita N, Nagatomo F, Murakami S, Kondo H, Ishihara A, Fujino H
    • Journal Title

      Scientific World Journal

      Volume: 2012 Pages: 637978-637978

    • DOI

      10.1100/2012/637978

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oxidative stress levels in rats depending on oxygen concentrations2012

    • Author(s)
      Nagatomo F, Fujino H, Kondo H, Ishihara A
    • Journal Title

      Oxid Med Cell Long

      Volume: 2012 Pages: 381763-381763

    • DOI

      10.1155/2012/381763

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of running exercise on oxidative capacity and PGC-1α mRNA levels in the soleus muscle of rats with metabolic syndrome2012

    • Author(s)
      Nagatomo F (1st author), Fujino H, Kondo H, Kouzaki K, Gu N, Takeda I, Tsuda K, Ishihara A
    • Journal Title

      Journal of Physiological Science

      Volume: 62 Issue: 2 Pages: 105-114

    • DOI

      10.1007/s12576-011-0188-1

    • NAID

      10030351596

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-fat diet-induced reduction of PGC-1α mRNA levels and oxidative capacity in the soleus muscle of rats with metabolic syndrome2012

    • Author(s)
      Nagatomo F (1st author), Fujino H, Kondo H, Takeda I, Tsuda K, Ishihara A
    • Journal Title

      Nutrition Research

      Volume: 32 Pages: 144-151

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PGC-1αmRNA level and oxidative capacity of the plantaris muscle in rats with metabolic syndrome, hypertension, and type 2 diabetes2011

    • Author(s)
      Nagatomo F, Fujino H, Kondo H, Gu N, Takeda I, Ishioka N, Tsuda K, Ishihara A:
    • Journal Title

      Acta Histochemica et Cytochemica

      Volume: 44 Pages: 73-80

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hyperbaric oxygen improves UVB irradiation-induced melanin pigmentation and diminishes senile spot size2011

    • Author(s)
      Nishizaka T, Nomura T, Sano T, Higuchi K, Nagatomo F, Ishihara A
    • Journal Title

      Skin Research and Technology

      Volume: 17 Pages: 332-338

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] PGC-1αand FOXO1 mRNA levels and fiber characteristics of the soleus and plantaris muscles in rats after hindlimb unloading2011

    • Author(s)
      Nagatomo F, Fujino H, Kondo H, Suzuki H, Kouzaki M, Takeda I, Ishihara A
    • Journal Title

      Histology and Histopathology

      Volume: 26 Pages: 1545-1553

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of exposure to hyperbaric oxygen on diabetes-induced cataracts in mice2011

    • Author(s)
      Nagatomo F, Roy RR, Takahashi H, Edgerton VR, Ishihara A
    • Journal Title

      Journal of Diabetes

      Volume: 3 Pages: 301-308

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regressed three-dimensional capillary network and inhibited angiogenic factors in the soleus muscle of non-obese rats with type 2 diabetes2011

    • Author(s)
      Kondo H, Fujino H, Murakami S, Nagatomo F, Roy RR, Ishihara A
    • Journal Title

      Nutrition and Metabolism

      Volume: 8 Pages: 77-77

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of hyperbaric oxygenation on blood pressure levels of spontaneously hypertensive rats2010

    • Author(s)
      Nagatomo F, Fujino H, Takeda I, Ishihara A
    • Journal Title

      Clinical and Experimental Hypertension

      Volume: 32 Pages: 193-197

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of exposure to hyperbaric oxygen on oxidative stress in rats with type II collagen-induced arthritis2010

    • Author(s)
      Nagatomo F, Gu N, Fujino H, Okiura T, Morimatsu F, Takeda I, Ishihara A
    • Journal Title

      Clinical and Experimental Medicine

      Volume: 10 Pages: 7-13

    • NAID

      120001887650

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 長期にわたる宇宙環境への滞在によるマウス脊髄運動ニューロンの変化.2012

    • Author(s)
      石原昭彦
    • Organizer
      第58 宇宙航空環境医学会大会
    • Place of Presentation
      豊橋市
    • Year and Date
      2012-11-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 長期にわたる宇宙滞在を目指して2012

    • Author(s)
      石原昭彦
    • Organizer
      第26回日本宇宙生物科学会学術集会.
    • Place of Presentation
      徳島市
    • Year and Date
      2012-09-29
    • Related Report
      2012 Final Research Report
  • [Presentation] シンポジウム. 長期にわたる宇宙滞在を目指して2012

    • Author(s)
      石原昭彦 (単独)
    • Organizer
      第26回日本宇宙生物科学会学術集会
    • Place of Presentation
      徳島市
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] シンポジウム. 長期にわたる宇宙環境への滞在によるマウス脊髄運動ニューロンの変化2012

    • Author(s)
      石原昭彦 (単独)
    • Organizer
      第58回日本宇宙航空環境医学会
    • Place of Presentation
      豊橋市
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 高気圧・高濃度酸素環境への滞在による2型糖尿病OLETFフットの高血糖抑制効果2011

    • Author(s)
      永友文子, 近藤浩代, 藤野英己, 顧寧, 武田功, 津田謹輔, 石原昭彦
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌市
    • Related Report
      2011 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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