| Project/Area Number |
22500732
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | University of Shizuoka |
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Principal Investigator |
MORITA Akihito 静岡県立大学, 食品栄養科学部, 助教 (40239653)
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 食素材 / イオンチャネル / 肥満 / 脂肪肝 / 地域特産品 / 体熱産生 / 温度センサー |
|---|
| Research Abstract |
Effects of cultivars in the Shizuoka area on the thermo-sensitive ion channels were investigated. The activity of thermo-sensitive TRPV1 or TRPA1 was measured after the addition of solvent extracts from wheat flour, Japanese pepper, onion, strawberry, scallion bakers garlic, and welsh onion. Although some extracts activate TRPV1 and/or TRPA1 channels, the components that activate these channels strongly, have not beenisolated. In order to investigate the preventive effects of these channel activatingcomponents on the fatty liver, acute alcoholic fatty liver model was created by the administration of ethanol into mice.
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