Project/Area Number |
22500775
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Eating habits, studies on eating habits
|
Research Institution | Tokai University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
SUZUKI Takayoshi 東海大学, 医学部, 准教授 (40287066)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | ヘリコバクター・ピロリ / 機能性食品 / 増殖抑制 / IL-8 / ピロリ菌 / ザクロ / 乳酸菌 |
Research Abstract |
Pomegranate juice suppressed growth of all the clinically separated strains of H. pylori and interleukin-8 secretion from stomach cells stimulated by the strains in vitro. As for the germless mice model infected with H. pylori, there were no obvious effects of pomegranate on the bacterial number in the stomach and anti-H. pylori titers in the serum, however, it might strengthen the growth inhibiting action of lactobachilus on H. pylori in the mice model.
|