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Search for biomarker of exposure to chemicals in diesel exhaust emission or Asian dust and health effect assessment of exposure to chemicals

Research Project

Project/Area Number 22510027
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental impact assessment/Environmental policy
Research InstitutionKanazawa University

Principal Investigator

MICHIGAMI Yoshimasa  金沢大学, 環境保全センター, 准教授 (90190678)

Co-Investigator(Kenkyū-buntansha) KAMBAYASHI Yasuhiro  金沢大学, 医学系, 講師 (20345630)
NAKAMURA Hiroyuki  金沢大学, 医学系, 教授 (30231476)
HITOMI Yoshiaki  金沢大学, 医学系, 准教授 (70231545)
Co-Investigator(Renkei-kenkyūsha) HIBINO Yuri  金沢大学, 医学系, 助教 (40362008)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords多環芳香族炭化水素類 / アレルギー疾患 / 大気汚染 / 環境 / 健康影響 / 黄砂
Research Abstract

The objectives of this study are the development of the method for polycyclic aromatic hydrocarbon (PAH) analysis to examine health effects of diesel exhaust emission and Asian dust (total suspended particulate: TSP) and the collection of basic data of change in TSP concentrations and PAH concentrations. Efficient analytical method of PAH in TSP was developed and data could be obtained using TSP which were collected everyday. The concentrations of TSP were higher in spring than in winter and the concentrations of PAH were higher in winter than in spring. The concentrations of TSP and PAH were higher when wind direction at maximum wind speed was southwest (containing south southwest and west southwest).

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (25 results)

All 2013 2012 2011 2010

All Journal Article (13 results) (of which Peer Reviewed: 13 results) Presentation (12 results)

  • [Journal Article] Limonene inhalation reduces allergic airway inflammation in Dermatophagoides farinae-treated mice2012

    • Author(s)
      Hirota R, Nakamura H, Bhatti SA, Ngatu NR, Muzembo BA, Dumavibhat N, Eitoku M, Sawamura M, Suganuma N
    • Journal Title

      Inhal Toxicol

      Volume: 24(6) Issue: 6 Pages: 373-381

    • DOI

      10.3109/08958378.2012.675528

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Obesity and aspirin intolerance are risk factors for difficult-to-treat asthma in Japanese non-atopic women2012

    • Author(s)
      Fukutomi Y, Taniguchi M, Tsuburai T,Tanimoto H, Oshikata C, Ono E, Sekiya K, Higashi N, Mori A, Hasegawa M, Nakamura H, Akiyama K
    • Journal Title

      ClinExp Allergy

      Volume: 42(5) Pages: 738-746

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Allergenicity and cross-reactivity of booklice (Liposcelis bostrichophila) : a common household insect pest in Japan2012

    • Author(s)
      Fukutomi.Y
    • Journal Title

      Int.Arch.Allergy Immunol.

      Volume: Vol.157 Issue: 4 Pages: 339-348

    • DOI

      10.1159/000329853

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between body mass index and asthma among Japanese adult : risk within normal weight range2012

    • Author(s)
      Fukutomi.Y
    • Journal Title

      Int.Arch.Allergy Immunol.

      Volume: Vol.157 Issue: 3 Pages: 281-287

    • DOI

      10.1159/000327555

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical relevance of IgE to recombinant Gly m 4 in the diagnosis of adult soybean allergy2012

    • Author(s)
      Fukutomi.Y
    • Journal Title

      J.Allergy Clin.Immunol.

      Volume: Vol.129 Issue: 3 Pages: 860-863

    • DOI

      10.1016/j.jaci.2012.01.031

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Differences in the Involvements of Loci of Promoter Region and Ile50Val in Interleukin-4 Receptor α Chain Gene between Atopic Dermatitis and Japanese Cedar Pollinosis2012

    • Author(s)
      Tanaka.T
    • Journal Title

      Allergology International

      Volume: 61 Issue: 1 Pages: 57-63

    • DOI

      10.2332/allergolint.10-OA-0302

    • NAID

      130004873044

    • ISSN
      1323-8930, 1440-1592
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Obesity and aspirin intolerance are risk factors for difficult-to-treat asthma in Japanese non-atopic women2012

    • Author(s)
      Fukutomi.Y
    • Journal Title

      Clin.Exp.Allergy

      Volume: Vol.42 Issue: 5 Pages: 738-746

    • DOI

      10.1111/j.1365-2222.2011.03880.x

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Time Trend in the Prevalence of Adult Asthma in Japan: Findings from Population-Based Surveys in Fujieda City in 1985, 1999, and 20062011

    • Author(s)
      Fukutomi.Y
    • Journal Title

      Allergology International

      Volume: 60 Issue: 4 Pages: 443-448

    • DOI

      10.2332/allergolint.10-OA-0282

    • NAID

      130004477104

    • ISSN
      1323-8930, 1440-1592
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Goishi tea consumption inhibits airway hyperresponsiveness in Balb/c mice2011

    • Author(s)
      Hirota R, Ngatu NR, Miyamura M, Nakamura H, Suganuma N
    • Journal Title

      BMC Immunol

      Volume: 12:45

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 環境衛生の面より考える思春期のアレルギー2011

    • Author(s)
      中村裕之,人見嘉哲,神林康弘,日比野由利,柴田亜樹,弘田量二,福富友馬,松崎一葉,烏帽子田彰
    • Journal Title

      思春期学

      Volume: 29(1) Pages: 1-8

    • NAID

      10028178575

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Goishi Tea Consumption Inhibits Airway Hyperresponsiveness in BALB/ c Mice2011

    • Author(s)
      Hirota R, Ngatu NR, Miyamura M, Nakamura H, Suganuma N
    • Journal Title

      BMC Immunology

      Volume: 12 Issue: 1 Pages: 45-45

    • DOI

      10.1186/1471-2172-12-45

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 環境衛生の面より考える思春期のアレルギー2011

    • Author(s)
      中村裕之
    • Journal Title

      思春期学Adolesentology

      Volume: 29 Pages: 1-8

    • NAID

      10028178575

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 抗酸化物質2:ビタミンE2010

    • Author(s)
      神林康弘
    • Journal Title

      日本予防医学会難誌

      Volume: 5 Pages: 3-10

    • NAID

      40017134909

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 浮遊粒子状物質濃度や多環芳香族炭化水素類濃度に影響する気象因子の検討2013

    • Author(s)
      神林康弘
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2013-03-26
    • Related Report
      2012 Final Research Report
  • [Presentation] 慢性咳嗽患者における黄砂のアレルギー症状への影響2013

    • Author(s)
      東朋美
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2013-03-26
    • Related Report
      2012 Final Research Report
  • [Presentation] 浮遊粒子状物質濃度や多環芳香族炭化水素類濃度に影響する気象因子の検討2013

    • Author(s)
      神林康弘
    • Organizer
      第83回日本衛生学会
    • Place of Presentation
      金沢大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] 慢性咳嗽患者における黄砂のアレルギー症状への影響2013

    • Author(s)
      東朋美
    • Organizer
      第83回日本衛生学会
    • Place of Presentation
      金沢大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] Characteristics of polycyclic aromatic hydrocarbons and heavy metals in total suspended particulate during Asian dust period in Japan2012

    • Author(s)
      Kambayashi Y
    • Organizer
      International Symposium Aerosols in East Asia and Their Impacts on Plants and Human Health
    • Place of Presentation
      東京
    • Year and Date
      2012-11-30
    • Related Report
      2012 Final Research Report
  • [Presentation] Health effect of Kosa aerosol2012

    • Author(s)
      Higashi T
    • Organizer
      International Symposium Aerosols in East Asia and Their Impacts on Plants and Human Health
    • Place of Presentation
      東京
    • Year and Date
      2012-11-30
    • Related Report
      2012 Final Research Report
  • [Presentation] 大気粉塵中多環芳香族炭化水素類と重金属の月変動および黄砂日の特徴2012

    • Author(s)
      神林康弘
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 黄砂による慢性咳嗽の症状への影響2012

    • Author(s)
      東朋美
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 大気粉塵中多環芳香族炭化水素類と重金属の月変動および黄砂日の特徴2012

    • Author(s)
      神林康弘
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都大学(京都府)
    • Year and Date
      2012-03-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 黄砂による慢性咳嗽の症状への影響2012

    • Author(s)
      東朋美
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都大学(京都府)
    • Year and Date
      2012-03-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Characteristics of polycyclic aromatic hydrocarbons and heavy metals in total suspended particulate during Asian dust period in Japan2012

    • Author(s)
      Kambayashi Y
    • Organizer
      International Symposium on Aerosols in East Asia and Their Impacts on Plants and Human Health
    • Place of Presentation
      東京農工大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] Health Effect of Kosa Aerosols2012

    • Author(s)
      Higashi T
    • Organizer
      International Symposium on Aerosols in East Asia and Their Impacts on Plants and Human Health
    • Place of Presentation
      東京農工大学
    • Related Report
      2012 Annual Research Report

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Published: 2010-11-30   Modified: 2019-07-29  

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