Development and evaluation of a novel method for inactivation of clinical wastewater based on electrolysis

• Project/Area Number: 22510091
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Environmental technology/Environmental materials
• Research Institution: Osaka Medical College
• Principal Investigator: NAKANO Takashi 大阪医科大学, 医学部, 准教授 (00257867)
• Co-Investigator(Kenkyū-buntansha): KOHNO Takehiro 大阪医科大学, 医学部, 准教授 (00319534)
• Co-Investigator(Renkei-kenkyūsha): WU Hong 大阪医科大学, 医学部, 助教 (80340553)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 環境負荷低減技術 / 水質汚濁・土壌汚染防止・浄化 / 抗菌薬・抗生物質 / 医療廃液 / 電気分解 / 抗ウイルス薬 / 環境技術 / 抗生物質

Research Abstract

We developed and evaluated a new method for inactivation of clinical wastewater based on electrolysis. We electrolyzed solutions of 10 groups of individual antibacterials, mixtures of them, and an antiviral drug, oseltamivir (TamifluTM). Almost all samples were able to inactivate by electrolysis. Furthermore, to develop a method for the detoxification of medicines in excreta, an antineoplastic solution in the presence of human urine was electrolyzed and evaluated. We found that the method can inactivate chemicals in urine, and succeeded to expand the application of this method.

Research Products

• [Journal Article] Application of electrolysis to inactivation of antibacterials in clinical use. (2013)
  • Author(s): Nakano, T., Hirose, J., Kobayashi, T., Hiro, N., Kondo, F., Tamai, K., Tanaka, K., and Sano, K.
  • Journal Title: Ecotoxicology and Environmental Safety Volume: 90 Pages: 98-102
  • Peer Reviewed
• [Journal Article] Disinfective process of strongly acidic electrolyzed product of sodium chloride solution against Mycobacteria. (2012)
  • Author(s): Matsushita Yamamoto, T., Nakano, T., Yamaguchi, M., Shimizu, M., Wu, H., Aoki, H., Ota, R., Kobayashi, T., and Sano, K.
  • Journal Title: Medical Molecular Morphology Volume: 45 Issue: 4 Pages: 199-205
  • DOI: 10.1007/s00795-011-0560-5
  • NAID: 10031137144
  • Peer Reviewed
• [Journal Article] Application of electrolysis for detoxification of an antineoplastic in urine. (2012)
  • Author(s): Kobayashi, T., Hirose, J., Sano, K., Kato, R., Ijiri, Y., Takiuchi, H., Tanaka, K., Goto, E., Tamai, H., and Nakano, T.
  • Journal Title: Ecotoxicology and Environmental Safety Volume: 78 Pages: 123-127
  • DOI: 10.1016/j.ecoenv.2011.11.028
  • Peer Reviewed
• [Journal Article] 電気分解の医療応用～医療と 環境～ (2010)
  • Author(s): 中野隆史 .
  • Journal Title: 大阪医科大学雑誌 Volume: 69巻 Pages: 125-138
  • NAID: 40018697322
• [Journal Article] 電気分解の医療応用～医療と環境～ (2010)
  • Author(s): 中野隆史
  • Journal Title: 大阪医科大学雑誌 Volume: 69 Pages: 125-138
  • NAID: 40018697322
• [Presentation] 電気分解によるオセルタミビル(タミフルR)の不活化. (2012)
  • Author(s): 中野隆 史 ,小林豊英,廣瀬潤,佐野浩一
  • Organizer: 第65回日本細菌学会関西支部総会.
  • Place of Presentation: 兵庫県神戸市
  • Year and Date: 2012-11-17
• [Presentation] 電気分解によるオセルタミビル（タミフル(R)）の不活化 (2012)
  • Author(s): 中野 隆史，小林 豊英，廣瀬 潤，佐野 浩一
  • Organizer: 日本細菌学会関西支部総会
  • Place of Presentation: 兵庫県神戸市 臨床研究情報センター（TRI）
• [Presentation] Inactivation of antibiotics inclinical wastewater by electrolysis. (2011)
  • Author(s): Nakano, T., Hirose, J., Kobayashi, T., Ijiri, Y., Kato, R., Hiro, N., Kondo, F., Ooi, Y., Yamamoto, T., Tanaka, K., and Sano, K.
  • Organizer: International Union of Microbiological Societies 2011 Congress (IUMS 2011: 国 際微生物学会議 2011).
  • Place of Presentation: 北海道札幌市
  • Year and Date: 2011-09-08
• [Presentation] Inactivation of antibiotics in clinical wastewater by electrolysis (2011)
  • Author(s): Nakano, T., Hirose, J., Kobayashi, T., Ijiri, Y., Kato, R., Hiro, N., Kondo, F., Ooi, Y., Yamamoto, T., Tanaka, K., Sano, K.
  • Organizer: IUMS 2011 (International Union of Microbiological Societies 2011 Congress)国際微生物学会議2011
  • Place of Presentation: 札幌コンベンションセンター
  • Year and Date: 2011-09-08
• [Presentation] 電気分解法を応用した抗菌薬含有医療廃液の不活化. (2010)
  • Author(s): 中 野 隆 史 ,廣瀬潤,小林豊英,井尻好雄, 加藤隆児,廣直樹,近藤文剛,大井幸昌,山本とも代,田中一彦,佐野浩一
  • Organizer: 第63回日本細菌学会関西支部総会
  • Place of Presentation: 大阪府枚方市
  • Year and Date: 2010-11-20
• [Presentation] 電気分解法を応用した抗菌薬含有医療廃液の不活化 (2010)
  • Author(s): 中野隆史, 他
  • Organizer: 第63回日本細菌学会関西支部総会
  • Place of Presentation: 関西医大枚方病院講堂(枚方市)
  • Year and Date: 2010-11-20
• [Remarks] 大阪医科大学微生物学教室WEBページ
  • URL: http://www.omc-m.org
• [Remarks] 大阪医科大学微生物学教室Webページ
  • URL: http://www.osaka-med.ac.jp/dens/mic/index-j.html
• [Remarks] 大阪医科大学微生物学教室WEBページ
  • URL: http://www.osaka-med.ac.jp/~micro/index-j.html