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Development of a high throughput screening chip for antigen-specific antibody-secreting cells

Research Project

Project/Area Number 22510128
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Microdevices/Nanodevices
Research InstitutionToyama Industrial Technology Center,

Principal Investigator

OBATA Tsutomu  富山県工業技術センター, 中央研究所, 副主幹研究員 (30416143)

Co-Investigator(Renkei-kenkyūsha) ONAGA Takashi  富山県工業技術センター, 中央研究所, 副主幹研究員
KISHI Hiroyuki  富山大学, 医学薬学研究部, 准教授 (60186210)
小岩 一郎  関東学院大学, 工学部, 教授 (40186599)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
KeywordsMEMS / バイオ / 免疫 / 抗体 / 細胞 / 免疫細胞 / マイクロチップ / 医療用デバイス / 抗原抗体反応
Research Abstract

We developed a high throughput screening chip for antigen-specific antibody-secreting cells. By forming the micro-wells and micro-magnetic spots on the chip, we realized high screening performance and cell utilization compared with the chip using a silicon substrate.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (21 results)

All 2013 2012 2011 Other

All Journal Article (1 results) Presentation (6 results) Patent(Industrial Property Rights) (14 results) (of which Overseas: 4 results)

  • [Journal Article] 医療用デバイスとめっきによる高機能化2011

    • Author(s)
      小幡勤
    • Journal Title

      表面技術

      Volume: 62巻 Pages: 625-629

    • NAID

      10030475707

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] ANALYSIS OF CELLULAR RESPONSES AT SINGEL CELL LEVELS WITH A HYBRID MAGNETIC MICROWELL ARRAY CHIP2012

    • Author(s)
      Hiroyuki Kishi, Tsutomu Obata, Sachiko Takami, Masayuki Kazui, Tatsuhiko Ozawa, Akio Ogawa, Atsushi Muraguchi
    • Organizer
      The 6th International Workshop on Approaches to Single-Cell Analysis
    • Place of Presentation
      京都リサーチパーク
    • Related Report
      2012 Annual Research Report
  • [Presentation] 抗原特異的抗体産生細胞スクリーニングチップの開発2011

    • Author(s)
      小幡勤
    • Organizer
      電気学会
    • Place of Presentation
      大阪大学(大阪府)
    • Year and Date
      2011-03-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 医療用デバイスとめっきによる高機能化2011

    • Author(s)
      小幡勤
    • Organizer
      表面技術協会 将来めっき技術検討部会
    • Place of Presentation
      大崎会館(東京都)
    • Year and Date
      2011-01-28
    • Related Report
      2012 Final Research Report
  • [Presentation] 医療用デバイスとめっきによる高機能化2011

    • Author(s)
      小幡勤
    • Organizer
      表面技術協会将来めっき技術検討部会
    • Place of Presentation
      大崎会館(東京都)
    • Year and Date
      2011-01-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 抗原特異的抗体産生細胞スクリーニングチップの開発2011

    • Author(s)
      小幡勤、高見幸子、岸裕幸
    • Organizer
      電気学会全国大会
    • Place of Presentation
      大阪大学 豊中キャンパス
    • Related Report
      2012 Final Research Report
  • [Presentation] ANALYSIS OF CELLULAR RESPONSES AT SINGEL CELL LEVELS WITH A HYBRID MAGNETIC MICROWELL ARRAY CHIP

    • Author(s)
      Hiroyuki Kishi, Tsutomu Obata, Sachiko Takami, Masayuki Kazui, Tatsuhiko Ozawa, Akio Ogawa, Atsushi Muraguchi
    • Organizer
      The 6th Inter national Workshop on Approaches to Single-Cell Analysis
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2013

    • Inventor(s)
      小幡勤
    • Industrial Property Rights Holder
      富山県
    • Filing Date
      2013-03-11
    • Related Report
      2012 Final Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2013

    • Inventor(s)
      小幡 勤
    • Industrial Property Rights Holder
      富山県
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-03-12
    • Related Report
      2012 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2012

    • Inventor(s)
      小幡勤
    • Industrial Property Rights Holder
      富山県
    • Industrial Property Number
      2012-163286
    • Filing Date
      2012-07-24
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2012

    • Inventor(s)
      小幡勤
    • Industrial Property Rights Holder
      富山県
    • Industrial Property Number
      2012-264012
    • Filing Date
      2012-12-03
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)]2012

    • Inventor(s)
      小幡勤、岸裕幸、高見幸子
    • Industrial Property Rights Holder
      富山県、富山大学
    • Acquisition Date
      2012-03-16
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2012

    • Inventor(s)
      小幡 勤
    • Industrial Property Rights Holder
      富山県
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-07-24
    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2012

    • Inventor(s)
      小幡 勤
    • Industrial Property Rights Holder
      富山県
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-12-03
    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2011

    • Inventor(s)
      小幡勤、岸裕幸、高見幸子
    • Industrial Property Rights Holder
      富山県、富山大学
    • Industrial Property Number
      2011-015652
    • Filing Date
      2011-01-27
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2011

    • Inventor(s)
      小幡勤、岸裕幸、高見幸子
    • Industrial Property Rights Holder
      富山県、富山大学
    • Industrial Property Number
      2011-219147
    • Filing Date
      2011-10-03
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2011

    • Inventor(s)
      小幡勤、岸裕幸、高見幸子
    • Industrial Property Rights Holder
      富山県、富山大学
    • Filing Date
      2011-11-22
    • Related Report
      2012 Final Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2011

    • Inventor(s)
      小幡勤, 岸裕幸, 高見幸子
    • Industrial Property Rights Holder
      富山県富山大学
    • Industrial Property Number
      2011-219147
    • Filing Date
      2011-10-03
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2011

    • Inventor(s)
      小幡勤, 岸裕幸, 高見幸子
    • Industrial Property Rights Holder
      富山県富山大学
    • Filing Date
      2011-11-22
    • Related Report
      2011 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2011

    • Inventor(s)
      小幡勤, 岸裕幸, 高見幸子
    • Industrial Property Rights Holder
      富山県富山大学
    • Filing Date
      2011-10-03
    • Acquisition Date
      2012-03-16
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] マイクロウェルアレイチップおよび細胞の回収方法2011

    • Inventor(s)
      小幡勤, 他二名
    • Industrial Property Rights Holder
      富山県富山大学SCW
    • Industrial Property Number
      2011-015652
    • Filing Date
      2011-01-27
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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