Study on the essential "suppression system of foreign genes" in bacteria
| Project/Area Number |
22510204
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Genome biology
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
KATO Junichi 首都大学東京, 大学院・理工学研究科, 教授 (10194820)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | ゲノム機能発現 / rRNA / プロセッシング / 大腸菌 / 必須遺伝子 / ゲノム / 染色体 / 外来遺伝子 / プロファージ |
|---|
| Research Abstract |
The important function of Escherichia coli Rho protein was recently found to be suppression of foreign genes. We analyzed the functions of uncharacterized essential genes, yqgF, yeaZ, ygjD, and yjeE. We found that YqgF, which is involved in transcriptional termination, is necessary for 16S rRNA processing and that yqgF, yeaZ, and ygjD are involved in transcriptional termination and genome integrity.
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Report
(4 results)
Research Products
(43 results)
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[Journal Article] Mutations in the essential Escherichia coli gene, yqgF, and their effects on transcription.2012
Author(s)
Iwamoto, A., Osawa, A., Kawai, M., Honda, H., Yoshida, S., Furuya, N., and Kato, J.
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Journal Title
J. Mol. Microbiol. Biotechnol.
Volume: 22
Pages: 17-23
Related Report
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[Journal Article] Effects on transcription of mutations in ygjD, yeaZ, and yjeE genes involved in a universal tRNA modification in Escherichia coli.2011
Author(s)
Hashimoto, C., Sakaguchi, K., Taniguchi, Y., Honda, H., Oshima, T., Ogasawara, N., and Kato, J.
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Journal Title
J. Bacteriol.
Volume: 193
Pages: 6075-6079
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