| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
In this study, we analyzed proteome expression pattern for multiple yeast species grown on different culture conditions to understand proteome differences involved in interspecies varieties. Eight yeast species grew with comparable growth rate on glucose medium. In contrast, four species of Saccharomyces genus, including S. cerevisiae, showed slow growth rate by two-to three-fold on glycerol and acetate medium, compared to four species belonging to different genus. Some groups of proteins involved in mitochondrial metabolic pathway and response to oxidative stress showed different abundance between Saccharomyces and other genus when grown on glycerol. It is suggested that such differences in abundance of proteins with specific functions could be responsible for disparity of growth rate among yeast species.
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