Project/Area Number |
22510227
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Living organism molecular science
|
Research Institution | Kanazawa University |
Principal Investigator |
SAKAMOTO Toshio 金沢大学, 自然システム学系, 准教授 (70324069)
|
Co-Investigator(Renkei-kenkyūsha) |
MATSUGO Seiichi 金沢大学, 自然システム学系, 教授 (30148126)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 生理活性物質 / 極限環境生物 / 抗酸化 / 紫外線 / 抗酸化活性 / 配糖体 / 細胞外マトリクス |
Research Abstract |
Mycosporine-like amino acids (MAAs) are water-soluble pigments that absorb UV radiation of 280 to 340 nm. In this study, novel MAAs were purified from the terrestrial cyanobacterium Nostoc commune, and their chemical structures were characterized. These unique glycosylated MAAs have multiple roles as a UV protectant and an antioxidant relevant to anhydrobiosis in this organism. Moreover, glycosylated MAA patterns could be a feasible chemotaxonomic marker for the characterization of the morphologically indistinguishable N. commune.
|