DEVELOPMENT OF NEW FUNCTIONAL MOLECULES BY POLYCYCLIC ALKALOIDS
| Project/Area Number |
22510239
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Living organism molecular science
|
|---|
| Research Institution | Hoshi University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 植物 / 生理活性 / 天然物 / アルカロイド / 創薬リード化合物 / 機能性分子 / 熱帯未利用植物資源 / 未利用植物資源 |
|---|
| Research Abstract |
Plants remain to this day one of the most important sources of biological active compounds and continue to provide drug discovery seeds. During our search for active ingredients from medicinal plants, we have isolated anti-malarial polycyclic alkaloids and limonoids with anti-lipid-droplets accumulation activity as new drug discovery seeds and evaluated their activities.
|
Report
(4 results)
Research Products
(36 results)
-
-
[Journal Article] New Limonoids from Chisocheton ceramicus2012
Author(s)
Wong Chin Piow, Misae Shimada, Alfarius Eko Nugroho, Yusuke Hirasawa, Toshio Kaneda, A. Hamid A. Hadi, Shirota Osamu and Hiroshi Morita, Ceramicines J-L
-
Journal Title
J. Nat. Med.
Volume: 66
Issue: 3
Pages: 566-570
DOI
Related Report
Peer Reviewed
-
[Journal Article] New Tricyclic Alkaloids, Cassiarins G, H, J, and K from Leaves of Cassia siamea2012
Author(s)
Jun Deguchi, Tomoe Hirahara, Yusuke Hirasawa, Wiwied Ekasari, Aty Widyawaruyanti, Osamu Shirota, Motoo Shiro, and Hiroshi Morita
-
Journal Title
Chemical and Pharmaceutical Bulletin
Volume: 60
Issue: 2
Pages: 219-222
DOI
NAID
ISSN
0009-2363, 1347-5223
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
[Journal Article] Ceramicines E-I, New Limonoids from Chisocheton ceramicus2011
Author(s)
Wong Chin Piow, Misae Shimada, Yuta Nagakura Alfarius Eko Nugruho, Yusuke Hirasawa, Toshio Kaneda, Khalijah Awang, A. Hamid A. Hadi, Khalit Mohamad, Motoo Shiro, and Hiroshi Morita
-
Journal Title
Chemical and Pharmaceutical Bulletin
Volume: 59
Issue: 3
Pages: 407-411
DOI
NAID
ISSN
0009-2363, 1347-5223
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
