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Study on the development and validation of behavioral intervention therapy program for psychiatric symptoms in dementia

Research Project

Project/Area Number 22530750
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Clinical psychology
Research InstitutionNagoya City University

Principal Investigator

SATO Junko  名古屋市立大学, 大学院・医学研究科, 研究員 (90566233)

Co-Investigator(Kenkyū-buntansha) NAKAAKI Shutaro  慶應義塾大学, 医学部, 特任准教授 (80315879)
MIMURA Masaru  慶応義塾大学, 医学部, 教授 (00190728)
TATSUMI Hiroshi  愛知学院大学, 心身科学部, 講師 (70514058)
古川 壽亮  名古屋市立大学, 大学院・医学研究科, 教授 (90275123)
Co-Investigator(Renkei-kenkyūsha) FURUKAWA Toshiaki  京都大学, 医学研究科, 教授 (90275123)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords認知症 / 精神症状 / 行動的介入療法 / 焦燥感 / 高次脳機能 / 非薬物療法
Research Abstract

Agitated behaviors are frequently observed in patients with dementia and can cause severe distress to caregivers. However, little evidence of the efficacy of nonpharmacological interventions for agitated behaviors exists in patients with dementia. The present pilot study aimed to evaluate the behavioral management technique (BMT) program developed by the Seattle Protocols for patients with agitated behaviors in Japan. Eighteen patients with dementia (Alzheimer’s disease, n = 14; dementia with Lewy bodies, n = 4) participated in an open study testing the effectiveness of the BMT program. The intervention consisted of 20 sessions over the course of three months. The primary outcomes were severity of agitation in dementia as measured using the Agitated Behavior in Dementia scale (ABID) and the Cohen-Mansfield Agitation Inventory (CMAI). The BMT program resulted in significant reductions in the total scores of both the ABID and CMAI. Although both the physically agitated behavior scores and the verbally agitated behavior scores of the ABID improved significantly, the psychosis symptoms did not improve after intervention. The BMT program is likely to be beneficial to caregivers suffering from distress as a result of agitated behaviors. In the future, a well-designed study to develop the BMT program more fully is needed.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (33 results)

All 2013 2012 2011 2010 Other

All Journal Article (16 results) (of which Peer Reviewed: 15 results) Presentation (8 results) Book (7 results) Remarks (2 results)

  • [Journal Article] Reduction in white matter before and after the development of delusions of theft in a patient with Alzheimer Disease .2013

    • Author(s)
      Nakaaki, S., Sato, J., Torii, K., Kawaguchi,T,Kawaguchi,A,,Narumoto. J.,Mimura, M.
    • Journal Title

      J Neuropsychiatry Clin Neursci

      Volume: (in press)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neuroanatomical abnormalities before the onset of different types of delusions in a patient with Alzheimer disease.2013

    • Author(s)
      Nakaaki, S., Sato, J., Torii, K., Kawaguchi,T,Kawaguchi,A,, Narumoto.J.,Mimura,M.
    • Journal Title

      J Neuropsychiatry Clin Neursci

      Volume: (in press)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Decreased white matter integrity before the onset of delusions in patients with Alzheimer's disease: diffusion tensor imaging.2013

    • Author(s)
      Nakaaki, S., Sato, J., Torii, K., Oka, M., Miyata, J., Mimura, M.
    • Journal Title

      Neuropsychiatric Disease and Treatment

      Volume: 9 Pages: 25-29

    • DOI

      10.2147/ndt.s38942

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neuroanatomical abnormalities before onset of delusions in patients with Alzheimer's disease: a voxel-based morphometry study.2013

    • Author(s)
      Nakaaki, S., Sato, J., Torii, K., Oka, M., Miyata, J., Mimura, M.
    • Journal Title

      Neuropsychiatric Disease and Treatment

      Volume: 9 Pages: 1-8

    • DOI

      10.2147/ndt.s38939

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Behavior management approach for agitated behavior in Japanese patients with dementia: a pilot study.2013

    • Author(s)
      Sato, J., Nakaaki, S., Torii, K.,Oka, M.,Mimura, M.
    • Journal Title

      Neuropsychiatric Disease and Treatment

      Volume: 9 Pages: 9-14

    • DOI

      10.2147/ndt.s38943

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neuroanatomical abnormalities before onset of delusions in patients with Alzheimer’s disease: a voxel-based morphometry study2013

    • Author(s)
      Shutaro Nakaaki
    • Journal Title

      Neuropsychiatric Disease and Treatment

      Volume: 9 Pages: 1-8

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Decreased white matter integrity before the onset of delusions in patients with Alzheimer’s disease: diffusion tensor imaging2013

    • Author(s)
      Shutaro Nakaaki
    • Journal Title

      Neuropsychiatric Disease and Treatment

      Volume: 9 Pages: 25-29

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Anosognosia: patients'distress and self-awareness of deficits in Alzheimer's disease2012

    • Author(s)
      Maki, Y., Amari, M., Yamaguchi, T., Nakaaki, S., Yamaguchi, H.
    • Journal Title

      Am J Alzheimers Dis Other Demen

      Volume: 27 Issue: 5 Pages: 339-45

    • DOI

      10.1177/1533317512452039

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neuropsychological and functional correlates of clock-drawing test in elderlyinstitutionalized patients with schizophrenia.2012

    • Author(s)
      Okamura, A., Kitabayashi, Y., Kohigashi, M., Shibata, K., Ishida, T., Narumoto, J.,Morioka, C., Kitabayashi, M., Kashima, A., Tani, N., Nakaaki S, Mimura M, Fukui, K.
    • Journal Title

      Psychogeriatrics

      Volume: 12 Pages: 242-7

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 失語症者の家族介護者におけるコミュニケーション自己効力感評価尺度2012

    • Author(s)
      辰巳 寛、山本 正彦、仲秋秀太郎、波多野 和夫
    • Journal Title

      高次脳機能研究

      Volume: 32 Pages: 514-524

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reliability and validity of the Japaneseversion of the Agitated Behaviour in Dementia Scale in Alzheimer's disease : three dimensions of agitated behaviour in dementia2011

    • Author(s)
      Torii Katsuyoshi
    • Journal Title

      Psychogeriatrics

      Volume: 11 Issue: 4 Pages: 212-220

    • DOI

      10.1111/j.1479-8301.2011.00371.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 認知症患者と家族の社会的孤立2011

    • Author(s)
      佐藤順子
    • Journal Title

      老年精神医学雑誌

      Volume: 22 Pages: 699-708

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Utility of the Quality of Life-Alzheimer's Disease Scale for mild cognitive impairment2011

    • Author(s)
      Hiroshi Tatsumi
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 65 Issue: 5 Pages: 533-533

    • DOI

      10.1111/j.1440-1819.2011.02245.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case with Hodgkin lymphoma and fronto-temporal lobular degeneration (FTLD)-like dementia facilitated by chemotherapy.2010

    • Author(s)
      Katsumata Ryuta
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 40 Pages: 365-368

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of mood : guides for clinicians2010

    • Author(s)
      Furukawa Toshiaki
    • Journal Title

      Journal of Psychosomatic Research

      Volume: 68 Pages: 581-589

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Factors of error and effort in memory intervention for patients with Alzheimer's disease and amnesic syndrome.2010

    • Author(s)
      Mimura Masaru
    • Journal Title

      Psychogeriatrics

      Volume: 10 Pages: 179-186

    • NAID

      10029771284

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 脳血流SPECT によるアルツハイマー病の焦燥感と関連する脳部位の検討.2012

    • Author(s)
      阪野公一, 仲秋秀太郎, 根木 惇, 鳥井勝義, 橋本伸彦, 佐藤順子,宮田 淳, 成本 迅, 明智龍男, 三村 將 .
    • Organizer
      第36回日本神経心理学会総会
    • Place of Presentation
      東京 学術総合センター
    • Year and Date
      2012-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 認知症の精神症状に対する行動的介入療法の検証-認知症 3 例に関する予備的な報告2012

    • Author(s)
      佐藤順子,仲秋秀太郎, 鳥井勝義, 阪野公一, 根木 惇, 宮 裕昭, 成本 迅, 山中克夫, 辰巳 寛, 三村 將
    • Organizer
      第27回日本老年精神医学会
    • Place of Presentation
      大宮ソニックシティ
    • Year and Date
      2012-06-21
    • Related Report
      2012 Final Research Report
  • [Presentation] 脳形態と拡散テンソル画像によるアルツハイマー病の精神症状出現予測の検討.2012

    • Author(s)
      仲秋秀太郎,佐藤順子,鳥井勝義,阪野公一,根木 惇,宮 裕昭,成本 迅, 山中克夫,辰巳 寛,宮田 淳,川口毅恒,三村 將
    • Organizer
      第27回日本老年精神医学会
    • Place of Presentation
      大宮ソニックシティ
    • Year and Date
      2012-06-21
    • Related Report
      2012 Final Research Report
  • [Presentation] 認知症の精神症状に対する行動的介入療法の効果研究.2012

    • Author(s)
      佐藤順子, 仲秋秀太郎, 鳥井勝義, 阪野公一, 根木 惇, 辰巳 寛, 三村 將
    • Organizer
      第13回日本認知症ケア学会
    • Place of Presentation
      アクトシティ浜松
    • Year and Date
      2012-06-20
    • Related Report
      2012 Final Research Report
  • [Presentation] 認知症の精神症状に対する行動的介入療法の効果研究2012

    • Author(s)
      佐藤順子
    • Organizer
      第13回日本認知症ケア学会
    • Place of Presentation
      アクトシティ浜松 (静岡県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 認知症の精神症状に対する行動的介入療法の検証-認知症3例に関する予備的な報告-2012

    • Author(s)
      佐藤順子
    • Organizer
      第27回日本老年精神医学会
    • Place of Presentation
      大宮ソニックシティ (埼玉県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 患者と家族への統合的介入方法による認知症患者とQOLに与える影響の検討2011

    • Author(s)
      佐藤順子
    • Organizer
      第26回日本老年精神医学会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2011-06-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 軽度認知障害(MCI)におけるQuality of Life(QOL)の特徴と関連要因について2010

    • Author(s)
      辰巳寛
    • Organizer
      第29回日本認知症学会
    • Place of Presentation
      ウインクあいち(名古屋)
    • Year and Date
      2010-11-19
    • Related Report
      2010 Annual Research Report
  • [Book] コミュニュケーションからみた認知症2013

    • Author(s)
      佐藤順子, 仲秋秀太郎 . Alzheimer 病. 三村將, 飯干紀代子
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2012 Final Research Report
  • [Book] 認知症ハンドブック.2013

    • Author(s)
      仲秋秀太郎, 佐藤順子周辺症状 人物誤認. 中島健二, 天野直二, 下濱俊, 富本秀和, 三村將
    • Publisher
      医学書院
    • Related Report
      2012 Final Research Report
  • [Book] 認知症ハンドブック2013

    • Author(s)
      仲秋秀太郎. 周辺症状 .実行機能障害. 中島健二, 天野直二, 下濱俊, 富本秀和, 三村將
    • Publisher
      医学書院
    • Related Report
      2012 Final Research Report
  • [Book] 記憶障害. 脳とこころのプライマリケア 第2巻 知能の衰え. 池田学 編2013

    • Author(s)
      仲秋秀太郎, 三村 將
    • Publisher
      シナジー出版社
    • Related Report
      2012 Final Research Report
  • [Book] コミュニュケーションからみた認知症.2013

    • Author(s)
      佐藤順子
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2012 Annual Research Report
  • [Book] 精神科研修ノート2011

    • Author(s)
      仲秋秀太郎(笠井清登, 村井俊哉, 三村将, 等編)
    • Publisher
      診断と治療社
    • Related Report
      2011 Annual Research Report
  • [Book] 認知症 薬物療法2.周辺症状 最新精神医学・別冊 新しい診断と治療のABC 662010

    • Author(s)
      仲秋秀太郎(三村將編)
    • Publisher
      最新医学社
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.ncupsychiatry.com/

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.ncupsychiatry.com/

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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