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Development of fast and multi-functional biological analysis systembased on the ultra-micro droplet reaction place

Research Project

Project/Area Number 22550079
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Analytical chemistry
Research InstitutionTokyo Metropolitan University

Principal Investigator

UCHIYAMA Katsumi  首都大学東京, 都市環境科学研究科, 教授 (40151899)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsマイクロチップ / 微少液滴 / 生化学分析 / インクジェット / マイクロ・ナノビーズ / 微少液滴反応 / ナノ粒子 / フォトニックバンド / 酵素免疫測定法 / ナノバイオ / マイクロ・ナノデバイス / フォトニック結晶
Research Abstract

Micro-droplet reaction place was successfully developed by using ink-jet. Generation method of droplet from ink-jet was extensively analyzed and finally we have found the optimal conditions. By using droplet reaction system, size effect, which is the most important characteristics of micro-total analysis system, was realized. Using this droplet reaction system, measuring system for bio-samples using enzyme linked immune solvent assay was realized. The system for sample dispensing and measuring system for incident light fluorescent and chemiluminescence was developed. Then, three dimensional ordered structure with micro and nano beads was successfully developed and those structure were used for the novel analytical tool. ELISA using three dimensional ordered micro beads structure showed drastic increase in the detection sensitivity with 1/1000 reagent consumption when it was used as a reaction place. Finally, we have successfully fabricated photonic crystals with nano-bead and showed the possibility of material sensing by eyes.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (95 results)

All 2013 2012 2011 2010 Other

All Journal Article (16 results) (of which Peer Reviewed: 16 results) Presentation (68 results) (of which Invited: 2 results) Book (7 results) Remarks (1 results) Patent(Industrial Property Rights) (3 results)

  • [Journal Article] Fabrication of Micro Device for Rapid and High-Sensitive Bio-Analysis2013

    • Author(s)
      M Yang, T Yabe, Katsumi Uchiyama
    • Journal Title

      Journal of Solid Mechanics and Materials Engineering

      Volume: 7 Issue: 2 Pages: 199-205

    • DOI

      10.1299/jmmp.7.199

    • NAID

      130003366858

    • ISSN
      1880-9871
    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Separation and determination of dopamine and epinephrine in serum by capillary electrophoresis with inkjet introduction system2013

    • Author(s)
      Y Weng, H Zeng, Y Nakagawa, S Ikeda,F Chen, H Nakajima, Katsumi Uchiyama
    • Journal Title

      CHROMATOGRAPHY

      Volume: Vol.34, No.1 Pages: 33-40

    • NAID

      10031159495

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Generation of picoliter droplets of liquid for electrospray ionization with piezoelectric inkjet2013

    • Author(s)
      C Luo, Y Ma, H Li, F Chen,Katsumi UchiyamaDOI: 10.1002/jms.3159J-M Lin
    • Journal Title

      Journal of Mass Spectrometry

      Volume: 48(3) Issue: 3 Pages: 321-328

    • DOI

      10.1002/jms.3159

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A piezoelectric drop-on-demand generator for accurate samples in capillary electrophoresis2013

    • Author(s)
      F Chen, Y Zhang, Y Nakagawa, H Zeng, C Luo, H Nakajima,Katsumi Uchiyama,J-M Lin
    • Journal Title

      Talanta

      Volume: 107 Pages: 111-117

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Generation of picoliter droplets of liquid for electrospray ionization with piezoelectric inkjet2013

    • Author(s)
      C Luo, Y Ma, H Li, F Chen, K Uchiyama and J-M Lin
    • Journal Title

      J. Mass Spectrom.

      Volume: 48 Pages: 33-44

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A piezoelectric drop-on-demand generator for accurate samples in capillary electrophoresis2013

    • Author(s)
      F Chen, Y Zhang, Y Nakagawa, H Zeng, C Luo, H Nakajima, K Uchiyama, J-M Lin
    • Journal Title

      Talanta

      Volume: 107 Pages: 321-328

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Accurate and Highly Reproducible Picoliter Injection System for Capillary Electrophoresis2012

    • Author(s)
      H Zeng , Y Weng , S Ikeda , Y Nakagawa , H Nakajima ,Katsumi Uchiyama
    • Journal Title

      Anal. Chem.

      Volume: 84 (24) Issue: 24 Pages: 10537-10542

    • DOI

      10.1021/ac302353q

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Determination of ammonium on an integrated microchip with LED-induced fluorescence detection2012

    • Author(s)
      Shuhua Xue,Katsumi Uchiyama,Hai-fang Li
    • Journal Title

      Journal of Environmental Sciences

      Volume: 24(3) Issue: 3 Pages: 564-570

    • DOI

      10.1016/s1001-0742(11)60802-4

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Controllable construction of ordered three-dimensional microbeads structure and its application in enzyme-linked immunosorbent microarray2012

    • Author(s)
      Hulie Zeng, Yoriko Inoue, Kosuke Moritani, Moeka Nishiwaki, Hizuru Nakajima, Katsumi Uchiyama
    • Journal Title

      Sensors and Acturators B: Chemical

      Volume: 168 Pages: 446-452

    • DOI

      10.1016/j.snb.2012.04.007

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of an automatic multi-channel ink-jet ejection chemiluminescence system and its application to the determination of horseradish peroxidase2012

    • Author(s)
      Fengming Chen, Zhen Lin, Yongzan Zheng, Hulie Zeng, Hizuru Nakajima,Katsumi Uchiyama, Jin-Ming Lin
    • Journal Title

      Analytica Chimica Acta

      Volume: 739 Pages: 77-82

    • DOI

      10.1016/j.aca.2012.06.022

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Accurate and Highly Reproducible Picoliter Injection System for Capillary Electrophoresis2012

    • Author(s)
      H Zeng , Y Weng , S Ikeda , Y Nakagawa , H Nakajima, and K Uchiyama
    • Journal Title

      Analytical Chemistry

      Volume: 84 Pages: 10537-10542

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Controllable construction of ordered three-dimensional microbeads structure and its application in enzyme-linked immunosorbent microarray2012

    • Author(s)
      H Zeng, Y Inoue, K Moritani, M Nishiwaki, H Nakajima, K Uchiyama
    • Journal Title

      Sensors and Actuators B

      Volume: 168 Pages: 446-452

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Performance of an organic photodiode as an optical detector and its application to fluorometric flow-immunoassay for IgA2012

    • Author(s)
      F Chen, Z Lin, Y Zheng, H Zeng, H Nakajima, K Uchiyama, J-M Lin
    • Journal Title

      Talanta

      Volume: 96 Pages: 132-139

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An integrated enzyme-linked immunosorbent assay system with an organic light-emitting diode and a chargecoupled device for fluorescence detection2011

    • Author(s)
      Hizuru Nakajima, Yukiko Okuma, Kazuhiri Morioka, Mayo Miyake, Akihide Hemmi, Tatsuya Tobita, Masayuki yahiro, Daisuke Yokoyama, Chihaya Adachi, Nobuaki Soh, Koji Nakano, Shuhua Xue, Hulie Zeng, Katsumi Uchiyama, Toshihiko Imato
    • Journal Title

      Journal of Separation Science

      Volume: 34 Pages: 2906-2912

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A surface plasmon resonance sensor on a compact disk-type microfluidic device2011

    • Author(s)
      Akihide Henmi, et al
    • Journal Title

      J Separation Science

      Volume: 34 Issue: 20 Pages: 2913-2919

    • DOI

      10.1002/jssc.201100446

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] インクジェットを用いる迅速平衡ヘッドスペース法の開発と水中揮発性有機化合物分析への適用2010

    • Author(s)
      清野信子、金子裕司、中嶋秀、内山一美
    • Journal Title

      分析化学

      Volume: 59 Pages: 619-625

    • NAID

      10030698653

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Quantitative Ink-Jet Injection for Capillary Electrophoresism2013

    • Author(s)
      Y. Weng, H. Zeng, H. Nakajima, K. Uchiyama
    • Organizer
      PITTCON2013
    • Place of Presentation
      Philadelphia, Pennsylvania, USA
    • Year and Date
      2013-03-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of LED-Induced Fluorescence Detection System Using a Compact Disk-Type Microfluidic Device and Its Application to ELISA2013

    • Author(s)
      H. Nakajima, K. Morioka, A. Hemmi, H. Zeng, K. Uchiyama
    • Organizer
      PITTCON2013
    • Place of Presentation
      Philadelphia, Pennsylvania, USA
    • Year and Date
      2013-03-21
    • Related Report
      2012 Final Research Report
  • [Presentation] インクジェット試料導入法による定量的試料プラグの形成とその応用2012

    • Author(s)
      中川 ゆり,翁 瑩,陳 鳳明,曽 湖烈,中川 ゆり,翁 瑩,陳 鳳明,曽 湖烈,中嶋 秀,内山 一美
    • Organizer
      第32回キャピラリー電気泳動シンポジウム(SCE2012)
    • Place of Presentation
      (独)産業技術総合研究所 関西センター
    • Year and Date
      2012-11-08
    • Related Report
      2012 Final Research Report
  • [Presentation] Analytical application of ink-jet micro dispensing technology2012

    • Author(s)
      Yuri Nakagawa, Fengming Chen, Zeng Hulie, Hizuru Nakajima, Katsumi Uchiyama
    • Organizer
      2012 China-Japan-Korea Symposium on Analytical Chemistry
    • Place of Presentation
      Shanghai New International Expo Centre, Shanghai, China
    • Year and Date
      2012-10-17
    • Related Report
      2012 Final Research Report
  • [Presentation] Preparation of three dimensional micro-structures and its application to chemical analysis2012

    • Author(s)
      Katsumi Uchiyama
    • Organizer
      2012 China-Japan-Korea Symposium on Analytical Chemistry
    • Place of Presentation
      Shanghai New International Expo Centre, Shanghai, China
    • Year and Date
      2012-10-17
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of efficient bioassays based on the microfluidic technique2012

    • Author(s)
      Shuhua Xue, Hulie Zeng, Hizuru Nakajima,Katsumi Uchiyama
    • Organizer
      2012 China-Japan-Korea Symposium on Analytical Chemistry
    • Place of Presentation
      Shanghai New International Expo Centre, Shanghai, China
    • Year and Date
      2012-10-17
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of an automatic multi-channel ink-jet ejection chemiluminescence system and its application to the determination of horseradish peroxidase2012

    • Author(s)
      Fengming Chen, Zhen Lin, Hulie Zeng, Hizuru Nakajima,Katsumi Uchiyama
    • Organizer
      China-Japan-Korea Symposium on Analytical Chemistry
    • Place of Presentation
      Shanghai New International Expo Centre, Shanghai, China
    • Year and Date
      2012-10-17
    • Related Report
      2012 Final Research Report
  • [Presentation] An accurately tunable picoliter-droptlet generation based on inkjet piezoelectric technique and application as sample injector of capillary electrophoresis2012

    • Author(s)
      F. Chen, H. Zeng, H. Nakajima, K.Uchiyama
    • Organizer
      2012 Joint Seminar of Tokyo Metropolitan University and Tsinghua University
    • Place of Presentation
      Tokyo Metropolitan University Minamiosawa Campus
    • Year and Date
      2012-08-21
    • Related Report
      2012 Final Research Report
  • [Presentation] A simple microstructure based on capillary glass-PDMS chip for fast enzyme-linked immunoassay2012

    • Author(s)
      S. Xue, H. Zeng, H. Nakajima, K.Uchiyama
    • Organizer
      2012 Joint Seminar of Tokyo Metropolitan University and Tsinghua University
    • Place of Presentation
      Tokyo Metropolitan University Minamiosawa Campus
    • Year and Date
      2012-08-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of Accurate Sample Introduction System by Ink-jet for Capillary Electrophoresis2012

    • Author(s)
      Y. Weng, H. Zeng, H. Nakajima, K.Uchiyama
    • Organizer
      2012 Joint Seminar of Tokyo Metropolitan University and Tsinghua University
    • Place of Presentation
      Tokyo Metropolitan University Minamiosawa Campus
    • Year and Date
      2012-08-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Quantitative analysis of on-line concentration technique in capillary electrophoresis using inkjet microchip injection method2012

    • Author(s)
      Y. Nakagawa, W. Ying, S. Ikeda, N.Saito, H. Nakajima, K. Uchiyama
    • Organizer
      2012 Joint Seminar of Tokyo Metropolitan University and Tsinghua University
    • Place of Presentation
      Tokyo Metropolitan University Minamiosawa Campus
    • Year and Date
      2012-08-21
    • Related Report
      2012 Final Research Report
  • [Presentation] 規則配列マイクロビーズ構造体ドットを用いたELISA反応場の構築と評価2012

    • Author(s)
      森谷孝介, 中嶋 秀, 曽 湖烈, 内山一美
    • Organizer
      第72回分析化学討論会
    • Place of Presentation
      鹿児島大学郡元キャンパス・工学部
    • Year and Date
      2012-05-19
    • Related Report
      2012 Final Research Report
  • [Presentation] キャピラリー電気泳動におけるインクジェット試料導入法を用いた定量的オンライン濃縮(II)2012

    • Author(s)
      中川ゆり, 池田紗織. 翁 宝, 曽 湖烈. 中嶋 秀,内山一美
    • Organizer
      第72回分析化学討論会
    • Place of Presentation
      鹿児島大学郡元キャンパス・工学部
    • Year and Date
      2012-05-19
    • Related Report
      2012 Final Research Report
  • [Presentation] Enzyme-Linked Immunosorbent Assay on Temperature Responsive Filter2012

    • Author(s)
      Ying Weng, Katsumi Uchiyama, Hulie Zeng, Hizuru Nakajima
    • Organizer
      PITTCON2012
    • Place of Presentation
      Orlando, FL USA
    • Year and Date
      2012-03-15
    • Related Report
      2012 Final Research Report
  • [Presentation] Enzyme-Linked Immunosorbent Assay on Temperature Responsive Filter2012

    • Author(s)
      Ying Weng, Katsumi Uchiyama, Hulie Zeng, Hizuru Nakajima
    • Organizer
      Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (PITTCON2012)
    • Place of Presentation
      Orlando, FL USA
    • Year and Date
      2012-03-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Accurate Sample Introduction Method for Capillary Electrophoresis2012

    • Author(s)
      Hu-lie Zeng , Saori Ikeda, Hizuru Nakajima, Katsumi Uchiyama
    • Organizer
      PITTCON2012
    • Place of Presentation
      Orlando, FL USA
    • Year and Date
      2012-03-13
    • Related Report
      2012 Final Research Report
  • [Presentation] Accurate Sample Introduction Method for Capillary Electrophoresis2012

    • Author(s)
      Hu-lie Zeng, Saori Ikeda, Hizuru Nakajima, Katsumi Uchiyama
    • Organizer
      Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (PITTCON2012)
    • Place of Presentation
      Orlando, FL USA
    • Year and Date
      2012-03-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fabrication of Nano Array Structure for Transmission Type Surface Plasmon2012

    • Author(s)
      Takashi Usui, Akihide Hemmi, Hulie Zeng, Katsumi Uchiyama, Hizuru Nakajima
    • Organizer
      Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (PITTCON2012)
    • Place of Presentation
      Orlando, FL USA
    • Year and Date
      2012-03-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] Analytical application of ink-jet micro dispensing technology2012

    • Author(s)
      Katsumi Uchiyama
    • Organizer
      The 6th Shanghai International Symposium on Analytical Chemistry(Plenary lecture)
    • Place of Presentation
      Shanghai(China)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] キャピラリー電気泳動分析におけるインクジェット試料導入法の開発と応用2012

    • Author(s)
      内山一美、池田紗織、中川ゆり、中嶋秀、曾 湖烈
    • Organizer
      第19回クロマトグラフィーシンポジウム
    • Place of Presentation
      八王子学園都市センター
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] キャピラリーガスクロマトグラフィー用小型原子発光検出器の性能向上2011

    • Author(s)
      玉橋大樹、中嶋秀、内山一美
    • Organizer
      平成23年度日本分光学会年次講演会
    • Place of Presentation
      理化学研究所横浜研究所交流棟
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] キャピラリー電気泳動のためのインクジェット試料導入とその応用2011

    • Author(s)
      池田紗織, 中川ゆり, Zeng HULIE, 中嶋秀, 内山一美
    • Organizer
      第31回キャピラリー電気泳動シンポジウム(SCE2011)
    • Place of Presentation
      鶴岡メタボロームキャンパス
    • Year and Date
      2011-11-10
    • Related Report
      2012 Final Research Report
  • [Presentation] キャピラリー電気泳動のためのインクジェット試料導入とその応用2011

    • Author(s)
      池田紗織、中川ゆり、Zeng HULIE、中嶋秀、内山一美
    • Organizer
      第31回キャピラリー電気泳動シンポジウム(SCE2011)
    • Place of Presentation
      鶴岡メタボロームキャンパス(山形県)
    • Year and Date
      2011-11-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] An Accurate Sample Introduction System for Capillary Electrophoresis2011

    • Author(s)
      Hu-lie Zeng, Saori Ikeda, Hizuru Nakajama, Katsumi Uchiyama
    • Organizer
      2011 China-Japan-Korea Symposium of Analytical Science on Food, Environmental and Nano-Technology(CJK2011)
    • Place of Presentation
      Jeju (Korea)
    • Year and Date
      2011-11-01
    • Related Report
      2012 Final Research Report
  • [Presentation] Enzyme-linked Immunosorbent Assay Based on Temperature Responsive Filter2011

    • Author(s)
      Ying Weng, Hulie Zeng, Hizuru Nakajima, Katsumi Uchiyama
    • Organizer
      2011 China-Japan-Korea Symposium of Analytical Science on Food, Environmental and Nano-Technology (CJK2011)
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2011-11-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] An Accurate Sample Introduction System for Capillary Electrophoresis2011

    • Author(s)
      Hu-lie Zeng, Saori Ikeda, Hizuru Nakajama, Katsumi Uchiyama
    • Organizer
      2011 China-Japan-Korea Symposium of Analytical Science on Food, Environmental and Nano-Technology (CJK2011)
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2011-11-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of Micro-Gas Chromatography System for On-Site Measurement2011

    • Author(s)
      Katsutni Uchiyama
    • Organizer
      2011 China-Japan-Korea Symposium of Analytical Science on Food, Environmental and Nano-Technology (CJK2011)
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2011-11-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] ポリジメチルシロキサン(PDMS)ウェルの作製と規則配列構造体ドットアレイを用いた反応場の評価2011

    • Author(s)
      森谷 孝介, 井上 依子, 中嶋 秀, 内山 一美
    • Organizer
      日本分析化学会第60 年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Year and Date
      2011-09-16
    • Related Report
      2012 Final Research Report
  • [Presentation] 3 次元オパール型フォトニック結晶の作製とその分析化学的応用2011

    • Author(s)
      新宮 正子, 井上 依子, 中嶋 秀, 内山 一美
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Year and Date
      2011-09-16
    • Related Report
      2012 Final Research Report
  • [Presentation] ポリジメチルシロキサン(PDMS)ウェルの作製と規則配列構造体ドットアレイを用いた反応場の評価2011

    • Author(s)
      森谷孝介・井上依子・中嶋秀・内山一美
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Year and Date
      2011-09-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 3次元オパール型フォトニック結晶の作製とその分析化学的応用2011

    • Author(s)
      新宮正子・井上依子・中嶋秀・内山一美
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Year and Date
      2011-09-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] シリカナノ粒子の調製と規則配列構造体による吸着測定2011

    • Author(s)
      井上 智之, 新宮 正子, 中嶋 秀, 内山 一美
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Year and Date
      2011-09-14
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] インクジェット試料導入法を用いた定量的オンライン濃縮2011

    • Author(s)
      中川 ゆり, 池田 紗織, 中嶋 秀, 内山 一美
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Year and Date
      2011-09-14
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] キャピラリー電気泳動分析のためのインクジェット試料導入法(その2)2011

    • Author(s)
      池田 紗織, 中川 ゆり, 斉藤 望, 中嶋 秀,内山 一美
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Year and Date
      2011-09-14
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] マイクロチップを用いるIgAのシークエンシャルインジェクション/蛍光イムノアッセイ2011

    • Author(s)
      温水香南・杉森康一・成瀬梓・石松亮一・中野幸二・中嶋秀・内山一美・辺見彰秀・今任稔彦
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Year and Date
      2011-09-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of 2D Surface Plasmon Resonance Sensor Using Multi Beam Splitter2011

    • Author(s)
      Akihide Hemmi, Ryuta Kawanishi, Noriaki Kaneki, Toshihiko Imato, Katsumi Uchiyama, Hizuru Nakajima
    • Organizer
      242nd American Chemical Society (ACS) National Meeting
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2011-09-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] キャピラリー電気泳動のためのインクジェット試料導入法2011

    • Author(s)
      池田 紗織, 中川 ゆり, 中嶋 秀, 内山 一美
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学 生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2012 Final Research Report
  • [Presentation] インクジェット試料導入法を用いた定量的オンライン濃縮2011

    • Author(s)
      池田 紗織, 中川 ゆり, 中嶋 秀, 内山 一美
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学 生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2012 Final Research Report
  • [Presentation] PDMSマイクロウェルの作製と規則配列構造体ドットアレイを用いた反応場の評価2011

    • Author(s)
      森谷孝介, 中嶋 秀,内山一美
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学 生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2012 Final Research Report
  • [Presentation] コンパクトディスク型マイクロチップを用いた表面プラズモンセンサの開発2011

    • Author(s)
      臼井崇・本朋紘・辺見彰秀・飛田達也・宗伸明・中野幸二・今任稔彦・内山一美・中嶋秀
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] 有機ELを光源とするマイクロチップ用蛍光検出システムの開発2011

    • Author(s)
      森岡和大・大隅夕紀子・宗伸明・中野幸二・今任稔彦・八尋正幸・安達千波矢・内山一美・中嶋秀
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] キャピラリー電気泳動のためのインクジェット試料導入法2011

    • Author(s)
      池田紗織・中川ゆり・中嶋秀・内山一美
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] インクジェット試料導入法を用いた定量的オンライン濃縮2011

    • Author(s)
      中川ゆり・池田紗織・斎藤望・中嶋秀・内山一美
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] ナノビーズ集積化フォトニック結晶の作製と簡易・迅速な免疫測定2011

    • Author(s)
      新宮正子・中嶋秀・内山一美
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] PDMSマイクロウェルの作製と規則配列構造体ドットアレイを用いた反応場の評価2011

    • Author(s)
      森谷孝介・中嶋秀・内山一美
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] 微小液滴の導入によるハロゲン化物の原子発光測定2011

    • Author(s)
      玉橋大樹・長野弾・中嶋秀・内山一美
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] シリカナノ粒子の調整と規則配列構造体による吸着測定2011

    • Author(s)
      井上智之・中嶋秀・内山一美
    • Organizer
      分離技術会年会2011
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2011-06-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fluorimetric detection system for micro-flow analysis using organic light emitting diode with spectrally narrow emission at cutoff wavelength from edge2011

    • Author(s)
      Yukiko Okuma, Nobuaki Soh, Koji Nakano, Hizuru Nakajima, Katsumi Uchiyama, Akihide Hemmi, Masayuki Yahiro, Chihaya Adachi, Toshihiko Imato
    • Organizer
      IUPAC International Congress on Analytical Sciences 2011(ICAS2011)
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2011-05-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] Chemiluminescence immunoassay on compact disk type microfluidic platform using magnetic microbeads based on sequential flow driven by centrifugal force2011

    • Author(s)
      Shuai Guo, Nobuaki Soh, Koji Nakano, Hizuru Nakajima, Katsumi Uchiyama, Akihide Hemmi, Kazuyoshi Yamasaki, Shigeharu Morooka, Toshihiko Imato
    • Organizer
      IUPAC International Congress on Analytical Sciences 2011(ICAS2011)
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2011-05-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] A surface plasmon resonance sensor fabricated on a compact disk-type microfluidic device2011

    • Author(s)
      Takashi Usui, Akihide Hemmi, Tatsuya Tobita, Akihiro Moto, Nobuaki Soh, Koji Nakano, Toshihiko Imato, Hizuru Nakajima, Katsumi Uchiyama
    • Organizer
      IUPAC International Congress on Analytical Sciences 2011(ICAS2011)
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2011-05-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of Micro-Gas Chromatography System for OnSite Environmental Measurement2011

    • Author(s)
      Katsumi Uchiyama
    • Organizer
      IUPAC International Congress on Analytical Sciences 2011(ICAS2011)
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2011-05-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fabrication of opal type photonic crystal and its application to sensing device2011

    • Author(s)
      Masako Aramiya, Yoriko Inoue, Hizuru Nakajima, Katumi Uchiyama
    • Organizer
      IUPAC International Congress on Analytical Sciences 2011(ICAS2011)
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2011-05-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of compact disk-type surface plasmon resonance immunosensor2011

    • Author(s)
      Akihide Hemmi, Takashi Usui, Akihiro Moto, Tatsuya Tobita, Nobuaki Soh, Koji Nakano, Toshihiko Imato, Katsumi Uchiyama, Hizuru Nakajima
    • Organizer
      The 6th International conference on Microtechnologies in Medicine and Biology (MMB2011)
    • Place of Presentation
      Lucerne, Switzerland
    • Year and Date
      2011-05-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] A surface plasmon resonance sensor on a compact disk-like microfluidic device2011

    • Author(s)
      Akihide Hemmi, Tatsuya Tobita, Takashi Usui, Akihiro Moto, NobuakiSoh, Koji Nakano, Toshihiko Imato, Katsumi Uchiyama, Hizuru Nakajima
    • Organizer
      Pittcon 2011, Atlanta
    • Place of Presentation
      Georgia, USA
    • Year and Date
      2011-03-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] An integrated fluorescence detection system using organic light emitting diodes as light source2010

    • Author(s)
      Mayo Miyake, Yukiko Okuma, Akihide Hemmi, Daisuke Yokoyama, Masayuki Yahiro, Chihaya Adachi, Toshihiko Imato, Katsumi Uchiyama, Hizuru Nakajima
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] A surface plasmon resonance sensor on a compact disk-like microfluidic device2010

    • Author(s)
      Akihide Hemmi, Takashi Usui, Akihiro Moto, Tatsuya Tobita, Toshihiko Imato, Katsumi Uchiyama, Hizuru Nakajima
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] インクジェット試料導入法を用いた定量的濃縮電気泳動法2010

    • Author(s)
      中川 ゆり,池田 紗織,斎藤 望,中嶋 秀,内山 一美
    • Organizer
      第30回キャピラリー電気泳動シンポジウム(SCE2010)
    • Place of Presentation
      長良川国際会議場
    • Year and Date
      2010-11-15
    • Related Report
      2012 Final Research Report
  • [Presentation] インクジェット試料導入法を用いた定量的濃縮電気泳動法2010

    • Author(s)
      中川ゆり, 池田紗織, 斎藤望, 中嶋秀, 内山一美
    • Organizer
      第30回キャピラリー電気泳動シンポジウム
    • Place of Presentation
      長良川国際会議場
    • Year and Date
      2010-11-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] キャピラリー電気泳動分析のためのインクジェット試料導入法2010

    • Author(s)
      池田 紗織, 斉藤 望, 中嶋 秀,内山一美
    • Organizer
      日本分析化学会第59 年会
    • Place of Presentation
      東北大学川内北キャンパス
    • Year and Date
      2010-09-16
    • Related Report
      2012 Final Research Report
  • [Presentation] キャピラリー電気泳動分析のためのインクジェット試料導入法2010

    • Author(s)
      池田紗織、斉藤望、中嶋秀、内山一美
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内北キャンパス
    • Year and Date
      2010-09-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Performance of microfludic platform fabricated on compact disk type chip and its application to flow analysis.2010

    • Author(s)
      郭帥、中嶋秀、辺見彰秀、山崎吉一、諸岡成治、宗伸明、中野幸二、内山一美、今任稔彦
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内北キャンパス
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] フィンガーサイズ原子発光検出器と液体クロマトグラフとの結合と元素選択的検出特性2010

    • Author(s)
      前多正明、齊藤和憲、内山一美、中釜達朗
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内北キャンパス
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] インクジェットによる原子発光分析装置のための新規試料導入法の開発2010

    • Author(s)
      長野弾, 玉橋大樹, 清野信子, 一之瀬達也, 中嶋秀, 内山一美
    • Organizer
      東京コンファレンス2010
    • Place of Presentation
      幕張メッセ国際会議場
    • Year and Date
      2010-09-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] インクジェットを用いる原子発光分析装置用試料導入システムの開発2010

    • Author(s)
      長野弾、籠田大介、清野信子、一之瀬達也、中嶋秀、内山一美
    • Organizer
      第71回分析化学討論会
    • Place of Presentation
      島根大学松江キャンパス
    • Year and Date
      2010-05-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] コンパクトディスク型マイクロチップを用いた表面プラズモン共鳴センサの開発2010

    • Author(s)
      臼井崇、本明紘、辺見彰秀、飛田達也、宗伸明、中野幸二、今任稔彦、中嶋秀、内山一美
    • Organizer
      第71回分析化学討論会
    • Place of Presentation
      島根大学松江キャンパス
    • Year and Date
      2010-05-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 微小液滴による迅速気液平衡の達成と分析化学的応用2010

    • Author(s)
      金子 裕司, 清野 信子, 中嶋 秀, 内山 一美
    • Organizer
      第77回日本分析化学会有機微量分析研究懇談会第83回計測自動制御学会力学量計測部会第27回合同シンポジウム
    • Place of Presentation
      京都大学百周年時計台記念館
    • Year and Date
      2010-05-14
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] 三次元オパール型フォトニック結晶の作製とストップバンドを利用したセンシング2010

    • Author(s)
      新宮 正子, 井上 依子, 中嶋 秀, 内山 一美
    • Organizer
      第77回日本分析化学会有機微量分析研究懇談会第83回計測自動制御学会力学量計測部会第27回合同シンポジウム
    • Place of Presentation
      京都大学百周年時計台記念館
    • Year and Date
      2010-05-14
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] ガスクロマトグラフィーによる有機微量元素分析を目指した有機化合物質の接触分解2010

    • Author(s)
      玉橋大樹、平野龍太郎、中嶋秀、内山一美
    • Organizer
      第77回日本分析化学会有機微量分析研究懇談会第83回計測自動制御学会力学量計測部会第27回合同シンポジウム
    • Place of Presentation
      京都大学百周年時計台記念館
    • Year and Date
      2010-05-14
    • Related Report
      2010 Annual Research Report
  • [Book] 分析化学実技シリーズ 機器分析編・7 ガスクロマトグラフィー2012

    • Author(s)
      内山一美, 小森享一
    • Total Pages
      189
    • Publisher
      共立出版株式会社
    • Related Report
      2012 Final Research Report
  • [Book] 分析化学実技シリーズ機器分析編・7ガスクロマトグラフィーExperts Series for Analytical Chemistry Istrumentation Analysis : Vol.7 Gas Chromatography2012

    • Author(s)
      内山一美、小森享一
    • Total Pages
      189
    • Publisher
      共立出版株式会社
    • Related Report
      2011 Annual Research Report
  • [Book] 分析化学用語辞典2011

    • Author(s)
      内山 一美, 中嶋 秀, 他55名
    • Total Pages
      451
    • Publisher
      株式会社オーム社
    • Related Report
      2012 Final Research Report
  • [Book] 基礎教育シリーズ,善木 道雄,寺前 紀夫,中釜 達朗,平山 和雄,三浦 恭之,南沢 宏明,森田 孝節分析化学〈基礎編〉2011

    • Author(s)
      本水 昌二,磯崎 昭徳,櫻川 昭雄,井原 敏博,内山 一美,善木 道雄,寺前 紀夫,中釜 達朗,平山 和雄,三浦 恭之,南沢 宏明,森田 孝節
    • Total Pages
      191
    • Publisher
      株式会社東京教学社
    • Related Report
      2012 Final Research Report
  • [Book] 基礎教育シリーズ分析化学<機器分析編>2011

    • Author(s)
      本水昌二、磯崎昭徳、櫻川昭雄、井原敏博、内山一美、善木道雄、寺前紀夫、中釜達朗、平山和雄、三浦恭之、南沢宏明、森田孝節
    • Publisher
      株式会社東京教学社
    • Related Report
      2011 Annual Research Report
  • [Book] 分析化学用語辞典2011

    • Author(s)
      内山一美、中嶋秀, 他55名
    • Total Pages
      451
    • Publisher
      株式会社オーム社
    • Related Report
      2011 Annual Research Report
  • [Book] ブルーバックスB-1692 新・材料化学の最前線 未来を創る「化学」の力2010

    • Author(s)
      首都大学東京都市環境学部分子応用科学研究会(分担)
    • Total Pages
      250
    • Publisher
      講談社ブルーバックス
    • Related Report
      2010 Annual Research Report
  • [Remarks] 首都大学東京 都市環境学部 分子応用化学域 内山研究室

    • URL

      http://www.comp.tmu.ac.jp/uchiyama/

    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] 三次元構造体の製造方法2012

    • Inventor(s)
      内山 一美, 中釜 達朗, 工藤祐生,西脇萌可, 井上依子, 清野信子, 友高正嗣, 相馬伸一
    • Industrial Property Rights Holder
      富士電機株式会社 ,公立大学法人首都大学東京
    • Filing Date
      2012-08-03
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 試料導入マイクロデバイス2011

    • Inventor(s)
      内山 一美, 中釜 達朗, 清野 信子, 篠田 正紀
    • Industrial Property Rights Holder
      富士電機株式会社 ,公立大学法人首都大学東京
    • Filing Date
      2011-11-25
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 試料導入マイクロデバイス2011

    • Inventor(s)
      内山 一美, 中釜 達朗, 清野 信子, 篠田 正紀
    • Industrial Property Rights Holder
      富士電機株式会社 ,公立大学法人首都大学東京
    • Filing Date
      2011-11-25
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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