| Project/Area Number |
22550104
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Fukuoka University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOGA Yuji 福岡大学, 理学部, 助教 (60373148)
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| Co-Investigator(Renkei-kenkyūsha) |
WAKITA Hisanobu 福岡大学, 理学部, 教授 (50078581)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 錯体・有機金属触媒 / 有機ニッケル触媒 / ニッケル２核錯体 / ニッケル１価錯体 / 触媒反応 / Kumadaカップリング / 触媒的アミノ化 / トリアリールアミン合成 / ニッケル1価錯体 / 協奏的触媒作用 / 2核錯体 / Kumadaクロスカップリング / Buchwald-Hartwigアミン化 / 反応機構解明 / ハロゲン化アリール |
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| Research Abstract |
Clarification of detailed concerted mechanism in the catalytic cross-coupling reactions of aryl halides using monovalent dinickel(I) complex bearing N-heterocyclic carbene, and development of versatile catalytic process have been achieved. (1) First, dinickel(I) intermediary compounds were isolated and determined, and EXAFS and XANES spectra were recorded to determine the structure of them. (1) Mechanistic consideration revealed that a redox cycle between Ni(I)-Ni(I) and Ni(II)-Ni(II) is possible during the catalytic reactions. (2) Buchwald-Hartwig amination of aryl halides with less reactive biarylamines proceeds even at room temperature. (3) Stable and reactive catalyst precursors of nickel(I) are prepared.
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