Development of Novel Amphiphilic Polymers for the Promotion of Oxidation Reactions in Aqueous Media

• Project/Area Number: 22550115
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Polymer chemistry
• Research Institution: Osaka Institute of Technology
• Principal Investigator: MASUYAMA Araki 大阪工業大学, 工学部, 教授 (30157218)
• Co-Investigator(Kenkyū-buntansha): KOBAYASHI Shoji 大阪工業大学, 工学部, 講師 (30374903)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 機能性高分子 / グリーンケミストリー / Oxone / 酸化反応 / エポキシ化反応 / 両親媒性樹脂 / 水媒質中の有機反応 / 機能性樹脂 / 水系での有機反応

Research Abstract

New amphiphilic cross-linked polystyrene-based copolymersbearing carbonyl groups in the grafted chains of the copolymers were designed andprepared. These copolymer-resins were significantly effective as reaction sites to promotethe epoxidation reactions of various alkenes by Oxone inside their polymer matrices inwater. The optimum structure of the copolymers and the optimum reaction conditions wereestablished. Through this research project, we can propose new highly secure methodologyfor oxidation reaction in aqueous media.

Research Products

• [Journal Article] Evaluation of cyclopentyl methyl ether (CPME) as a solvent for radical reactions (2013)
  • Author(s): S. Kobayashi, H. Kuroda, Y. Ohtsuka, T. Kashihara, A. Masuyama, K.Watanabe
  • Journal Title: Tetrahedron Volume: Vol.69 Issue: 10 Pages: 2251-2259
  • DOI: 10.1016/j.tet.2013.01.030
  • Peer Reviewed
• [Journal Article] 〓Total synthesis and structural revision of hericerin (2012)
  • Author(s): S. Kobayashi, T. Inoue, A. Ando, H.Tamanoi, I. Ryu, A. Masuyama
  • Journal Title: J. Org. Chem. Volume: Vol.77 Issue: 13 Pages: 5819-5822
  • DOI: 10.1021/jo300719m
  • Peer Reviewed
• [Journal Article] Stereocontrolled synthesis of substituted bicyclic ethers through oxy-Favorskii rearrangement: Total synthesis of (±)-Communiol E (2011)
  • Author(s): S. Kobayashi, T. Kinoshita, T.Kawamoto, M. Wada, H. Kuroda, A.Masuyama, I. Ryu
  • Journal Title: J. Org. Chem. Volume: Vol.76 Issue: 17 Pages: 7096-7103
  • DOI: 10.1021/jo201064h
  • Peer Reviewed
• [Journal Article] Rapid Access to 6-Bromo-5,7-Dihydroxyphthalide 5-Methyl ether by a CuBr_2-Mediated Multi-step Reaction : Concise Total Syntheses of Hericenone J and 5'-Deoxohericenone C (hericene A) (2011)
  • Author(s): Kobayashi, S.; Ando, A.; Kuroda, H.; Ejima, S.; Masuyama, A.; Ryu, I.
  • Journal Title: Tetrahedron Volume: 67 Issue: 47 Pages: 9087-9092
  • DOI: 10.1016/j.tet.2011.09.104
  • Peer Reviewed
• [Presentation] 水媒質中でのOxone酸化を促進する機能性両親媒性樹脂の構造最適化 (2013)
  • Author(s): 田中,小林,益山
  • Organizer: 日本化学会第93春季年会
  • Place of Presentation: 立命館大学びわこ・くさつキャンパス.
  • Year and Date: 2013-03-24
• [Presentation] 新規両親媒性α-アルコキシアルキルヒドロペルオキシド(α-AHP)の合成と機能 (2011)
  • Author(s): 麻原,手嶋,小林,益山
  • Organizer: 日本油化学会フレッシュマンサミットOSAKA
  • Place of Presentation: 近畿大学本部キャンパス.
  • Year and Date: 2011-11-05
• [Presentation] 新規両親媒性α-アルコキシアルキルヒドロペルオキシド(α-AHP)の合成と機能 (2011)
  • Author(s): 麻原啓太・手嶋彩由里・小林正治・益山新樹
  • Organizer: 日本油化学会フレッシュマンサミットOSAKA
  • Place of Presentation: 近畿大学本部キャンパス(東大阪市)
  • Year and Date: 2011-11-05
• [Presentation] 機能性両親媒性樹脂を反応場とするOxone水溶液によるオレフィンのエポキシ化 (2010)
  • Author(s): 狩野,細川,岡田,益山
  • Organizer: 日本油化学会第49回年会
  • Place of Presentation: 北海道大学函館キャンパス.
  • Year and Date: 2010-09-16
• [Presentation] 機能性両親媒性樹脂を反応場とするOxone水溶液によるオレフィンのエポキシ化 (2010)
  • Author(s): 狩野亮・細川長幹・岡田朋久・益山新樹
  • Organizer: 日本油化学会第49回年会
  • Place of Presentation: 北海道大学函館キャンパス(北海道)
  • Year and Date: 2010-09-16
• [Presentation] 水媒質中での Oxone 酸化を促進する機能性両親媒性樹脂の構造最適化
  • Author(s): 田中 淳・小林正治・益山新樹
  • Organizer: 日本化学会 第 93 春季年会
  • Place of Presentation: 立命館大学 びわこ・くさつキャンパス（滋賀県）
• [Remarks]
  • URL: http://www.oit.ac.jp/chem/cherry/2_lab/
• [Remarks] 大阪工業大学工学部応用化学科 物質生命化学研究室ホームページ
  • URL: http://www.oit.ac.jp/chem/cherry/2_lab/
• [Remarks]
  • URL: http://www.oit.ac.jp/chem/cherry/2_lab/
• [Remarks]
  • URL: http://www.oit.ac.jp/chem/cherry/2_lab/