Carboxylation by decarboxylases using supercritical and high-pressure carbon dioxide
| Project/Area Number |
22550139
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental chemistry
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
MATSUDA Tomoko 東京工業大学, 大学院・生命理工学研究科, 講師 (10319494)
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| Co-Investigator(Kenkyū-buntansha) |
YAMANAKA Rio 姫路獨協大学, 薬学部, 講師 (40454764)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | グリーンケミストリー / 超臨界二酸化炭素 / 酵素反応 / 二酸化炭素排出削減 / 合成化学 / 化学工業 / 脱炭酸酵素 / カルボキシル化反応 / 環境技術 |
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| Research Abstract |
Carboxylation using decarboxylases such as a malate dehydrogenase and an isocitrate dehydrogenase had been investigated to establish an efficient production method for the useful materials. Overexpression of a stable enzyme has been achieved. Furthermore, efficient carboxylation reaction using the enzyme was also successful established.
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Report
(4 results)
Research Products
(54 results)
