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DEVELOPMENT OF NANOCOMPOSITE MATERIALS FOR MEDICAL DRESSING

Research Project

Project/Area Number 22550197
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Polymer/Textile materials
Research InstitutionTottori University

Principal Investigator

SAIMOTO Hiroyuki  鳥取大学, 大学院・工学研究科, 教授 (20186977)

Co-Investigator(Renkei-kenkyūsha) MINAMI Saburo  鳥取大学, 農学部, 教授 (70032307)
MORIMOTO Minoru  鳥取大学, 生命機能研究支援センター, 准教授 (10273880)
IFUKU Shinsuke  鳥取大学, 大学院・工学研究科, 准教授 (70402980)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywordsキチン / キトサン / 医用接着材 / シーリング材料 / 多重分岐キトサン / カルボキシメチルキチン / 医用接着剤
Research Abstract

Compared with hyperbranched chitosan derivatives, anionic chitin derivatives showed better dispersion performance in chitin nanofiber suspension. Adhesion properties were evaluated by using collagen films. Newly developed nanocomposite materials consist of chitin derivatives and chitin nanofibers showed promising adhesion properties.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (50 results)

All 2013 2012 2011 2010 Other

All Journal Article (23 results) (of which Peer Reviewed: 23 results) Presentation (19 results) (of which Invited: 2 results) Book (2 results) Remarks (2 results) Patent(Industrial Property Rights) (4 results)

  • [Journal Article] Chitin Nanofibers: Preparations, Modifications, and Applications2012

    • Author(s)
      S.Ifuku, H. Saimoto
    • Journal Title

      Nanoscale

      Volume: 4 Issue: 11 Pages: 3308-3318

    • DOI

      10.1039/c2nr30383c

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of organosoluble chitosan derivatives with polyphenolic side chains2012

    • Author(s)
      M. Morimoto, T. Nakajima, M.Ishikura, Y. Shigemasa, S. Ifuku, H.Saimoto
    • Journal Title

      Carbohydrate Polymers

      Volume: 90(3) Issue: 3 Pages: 1259-1264

    • DOI

      10.1016/j.carbpol.2012.06.067

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A short synthesis of highly soluble chemoselective chitosan derivatives via "click chemistry"2012

    • Author(s)
      S. Ifuku, M.Wada, M. Morimoto, H. Saimoto
    • Journal Title

      Carbohydrate Polymers

      Volume: 90 Issue: 2 Pages: 1182-1186

    • DOI

      10.1016/j.carbpol.2012.06.074

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nano-fibrillation of dry chitin powder by Star Burst system2012

    • Author(s)
      S. Ifuku, K.Yamada, M. Morimoto, H. Saimoto
    • Journal Title

      Journal of Nanomaterials

      Volume: 2012 Issue: 1 Pages: 1-7

    • DOI

      10.1155/2012/645624

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Graft polymerization of acrylic acid onto chitin nanofiber to improve dispersibility in basic water2012

    • Author(s)
      S.Ifuku, M. Iwasaki, M. Morimoto, H.Saimoto
    • Journal Title

      Carbohydrate Polymers

      Volume: 90(1) Issue: 1 Pages: 623-627

    • DOI

      10.1016/j.carbpol.2012.05.087

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] α -Chitin nanofibrils improve inflammatory and fibrosis responses in inflammatory bowel disease mice model2012

    • Author(s)
      K. Azuma, T. Osaki,S. Ifuku, H.Saimoto, T. Tsuka, T. Imagawa, Y.Okamoto, S. Minami
    • Journal Title

      Carbohydrate Polymers

      Volume: 90(1) Issue: 1 Pages: 197-200

    • DOI

      10.1016/j.carbpol.2012.05.023

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of polysilsesquioxane-urethaneacrylate copolymer film reinforced with chitin nanofibers2012

    • Author(s)
      S.Ifuku, A. Ikuta, T. Hosomi, S. Kanaya, Z. Shervani, M. Morimoto, H. Saimoto
    • Journal Title

      Carbohydrate Polymers

      Volume: 89(3) Issue: 3 Pages: 865-869

    • DOI

      10.1016/j.carbpol.2012.04.022

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial and preventive effect of chitin nanofibers in a dextran sulfate sodium-induced acute ulcerative colitis model2012

    • Author(s)
      K. Azuma, T. Osaki, T.Wakuda,S. Ifuku, H. Saimoto, T.Imagawa, Y. Okamoto, S. Minami
    • Journal Title

      Carbohydrate Polymers

      Volume: 87(2) Issue: 2 Pages: 1399-1403

    • DOI

      10.1016/j.carbpol.2011.09.036

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial and preventive effect of chitin nanofibrils in a dextran sulfate sodiuminduced acute ulcerative colitis model2012

    • Author(s)
      K.Azuma
    • Journal Title

      Carbohydrate Polymers

      Volume: VOL.87 Pages: 1399-1403

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of chitin nanofibers from mushrooms2011

    • Author(s)
      S. Ifuku, R. Nomura, M.Morimoto, H. Saimoto
    • Journal Title

      Materials

      Volume: 4 Issue: 8 Pages: 1417-1425

    • DOI

      10.3390/ma4081417

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preparation and characterization of optically transparent chitin nanofiber/(meth)acrylic resin composites2011

    • Author(s)
      S.Ifuku, S. Morooka, A. N.Nakagaito, M. Morimoto, H. Saimoto
    • Journal Title

      Green Chemistry

      Volume: 13(7) Pages: 1708-1711

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of highly chemoselective N-phthaloyl chitosan in aqueous media2011

    • Author(s)
      S. Ifuku, T. Miwa, M.Morimoto, H. Saimoto
    • Journal Title

      Green Chemistry

      Volume: 13(6) Issue: 6 Pages: 1499-1502

    • DOI

      10.1039/c0gc00860e

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simple preparation method of chitin nanofibers from prawn shell under neutral conditions2011

    • Author(s)
      S. Ifuku,M. Nogi, K. Abe,M. Yoshioka, M. Morimoto, H. Saimoto,Hiroyuki Yano
    • Journal Title

      Carbohydr. Polym

      Volume: 84(2) Issue: 2 Pages: 762-764

    • DOI

      10.1016/j.carbpol.2010.04.039

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of Novel Chitosan with Chitosan Side Chains2011

    • Author(s)
      Minoru Morimoto, Masaru Nakao, Naoya Ishibashi, Yoshihiro Shigemasa, Shinsuke Ifuku, Hiroyuki Saimoto
    • Journal Title

      Carbohydr. Polym

      Volume: 84(2) Issue: 2 Pages: 727-731

    • DOI

      10.1016/j.carbpol.2010.03.035

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of Highly Regioselective Chitosan Derivatives via "Click Chemistry"2011

    • Author(s)
      S.Ifuku
    • Journal Title

      Carbohydrate Polymers

      Volume: VOL.85 Pages: 653-657

    • NAID

      10029509693

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of highly chemoselective N-phthaloyl chitosan in aqueous media2011

    • Author(s)
      S.Ifuku
    • Journal Title

      Green Chemistry

      Volume: VOL.13 Pages: 1499-1502

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation and characterization of optically transparent chitin nanofiber/(meth)acrylic resin composites2011

    • Author(s)
      S.Ifuku
    • Journal Title

      Green Chemistry

      Volume: VOL.13 Pages: 1708-1711

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of chitin nanofibers from mushrooms2011

    • Author(s)
      S.Ifuku
    • Journal Title

      Materials

      Volume: VOL.4 Pages: 1417-1425

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of Novel Chitosan with Chitosan Side Chains2011

    • Author(s)
      M.Morimoto
    • Journal Title

      Carbohydrate Polymers

      Volume: VOL.84 Pages: 727-731

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Simple preparation method of chitin nanofibers from prawn shell under neutral conditions2011

    • Author(s)
      S.Ifuku
    • Journal Title

      Carbohydrate Polymers

      Volume: VOL.84 Pages: 762-764

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acetylation of Chitin Nanofibers and their Transparent Nanocomposite Films2010

    • Author(s)
      S.Ifuku, S. Morooka, M.Morimoto, H. Saimoto
    • Journal Title

      Biomacromolecules

      Volume: 11(5) Issue: 5 Pages: 1326-1330

    • DOI

      10.1021/bm100109a

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fibrillation of dried chitin into 10-20 nm nanofibers by a simple grinding method under acidic conditions2010

    • Author(s)
      S.Ifuku
    • Journal Title

      Carbohydrate Polymers

      Volume: VOL.81 Pages: 134-139

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acetylation of Chitin Nanofibers and their Transparent Nanocomposite Films2010

    • Author(s)
      S.Ifuku
    • Journal Title

      Biomacromolecules

      Volume: VOL.11 Pages: 1326-1330

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Effect of Chitin Nanofibrils on Ulcerative Colitis Mouse Model and Its Mechanism2012

    • Author(s)
      S. Minami, K. Azuma, T. Osaki, T. Imagawa, T. Tsuka, Y. Okamoto, S. Ifuku, H. Saimoto
    • Organizer
      12th International Conference on Chitin and Chitosan
    • Place of Presentation
      Fortaleza, Brazil
    • Year and Date
      2012-09-03
    • Related Report
      2012 Final Research Report
  • [Presentation] キチンナノファイバーの皮膚に対する効果2012

    • Author(s)
      大崎智弘、伊藤育子、今川智敬、柄武志、岡本芳晴、伊福伸介、斎本博之、南三郎
    • Organizer
      第26回キチン・キトサンシンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2012-07-12
    • Related Report
      2012 Final Research Report
  • [Presentation] Effects of chitin nanofibrils on skin2012

    • Author(s)
      Tomohiro Osaki
    • Organizer
      26th Symposium on Chitin and Chitosan
    • Place of Presentation
      Hokkaido University, Japan
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Anti-inflammatory effect of chitin nanofiber on ulcerative colitis mouse model2012

    • Author(s)
      Kazuo Azuma
    • Organizer
      26th Symposium on Chitin and Chitosan
    • Place of Presentation
      Hokkaido University, Japan
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Preparation of highly regioselective chitosan derivatives via "click chemistry"2012

    • Author(s)
      Chisato Matumoto
    • Organizer
      26th Symposium on Chitin and Chitosan
    • Place of Presentation
      Hokkaido University, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effect of chitin nanofibrils on ulcerative colitis mouse model and mechanism2012

    • Author(s)
      Saburo Minami
    • Organizer
      12th International Conference on Chitin and Chitosan
    • Place of Presentation
      Fortareza, Brazil
    • Related Report
      2012 Annual Research Report
  • [Presentation] Preparation of optically transparent chitin nanofiber/polysilsesquioxane composites2012

    • Author(s)
      Shinsuke Ifuku
    • Organizer
      12th International Conference on Chitin and Chitosan
    • Place of Presentation
      Fortareza, Brazil
    • Related Report
      2012 Annual Research Report
  • [Presentation] クリックケミストリーを利用した高位置選択的キトサン誘導体の調製2011

    • Author(s)
      和田昌浩、松本智里、伊福伸介、森本稔、斎本博之
    • Organizer
      第25回キチン・キトサンシンポジウム
    • Place of Presentation
      奈良
    • Year and Date
      2011-08-31
    • Related Report
      2012 Final Research Report
  • [Presentation]2011

    • Author(s)
      南三郎、大崎智弘、今川智敬、柄武志、岡本芳晴、伊福伸介、斎本博之
    • Organizer
      第25回キチン・キトサンシンポジウム
    • Place of Presentation
      奈良
    • Year and Date
      2011-08-31
    • Related Report
      2012 Final Research Report
  • [Presentation] キチンナノファイバーの製造とその利用開発2011

    • Author(s)
      伊福伸介、森本稔、斎本博之
    • Organizer
      第25回キチン・キトサンシンポジウム
    • Place of Presentation
      奈良
    • Year and Date
      2011-08-30
    • Related Report
      2012 Final Research Report
  • [Presentation] Synthesis of organosoluble chitosan derivatives with polyphenolic side chains2011

    • Author(s)
      H. Saimoto
    • Organizer
      10thInternational Conference of European Chitin Society
    • Place of Presentation
      St. Petersburg, Russia
    • Year and Date
      2011-05-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Synthesis of new chitosan derivatives by a regioselective Mannich reaction2011

    • Author(s)
      H.Saimoto
    • Organizer
      10th international conference of the European chitin society
    • Place of Presentation
      Saint-Petersburg (Russia)
    • Year and Date
      2011-05-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] Synthesis of soluble chitosan derivatives with polyphenolic side chains2010

    • Author(s)
      M. Morimoto, T. Tonoi, Y. Hakone, S.Ifuku, H. Saimoto
    • Organizer
      The 2nd International and Cross-Strait Chitin and Chitosan Symposium
    • Place of Presentation
      Qianjiang, China
    • Year and Date
      2010-11-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Synthesis of soluble chitosan derivatives with polyphenolic side chains2010

    • Author(s)
      H.Saimoto
    • Organizer
      2nd international and cross-strait chitin and chitosan symposium
    • Place of Presentation
      Qianjiang (China)(招待講演)
    • Year and Date
      2010-11-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 水系でのキトサンのフタロイル化2010

    • Author(s)
      三輪剛士、伊福伸介、森本稔、斎本博之
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-07-14
    • Related Report
      2012 Final Research Report
  • [Presentation] 乾燥キチンからの簡便なナノファイバー製造技術とその透明複合フィルムの開発2010

    • Author(s)
      伊福伸介、吉岡勝史、森本稔、斎本博之
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-07-13
    • Related Report
      2012 Final Research Report
  • [Presentation] CM-キチンを用いた光硬化性キチン誘導体の合成2010

    • Author(s)
      山本知加子、寺田敦、石橋直也、伊福伸介、森本稔、斎本博之
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-07-13
    • Related Report
      2012 Final Research Report
  • [Presentation] Poly-NIPAmをグラフとしたキチンナノファイバーの調製2010

    • Author(s)
      岩崎暢昌、伊福伸介、森本稔、斎本博之
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-07-13
    • Related Report
      2012 Final Research Report
  • [Presentation] キチンナノファイバー補強透明ナノコンポジットのキャラクタリゼーション2010

    • Author(s)
      諸岡慎、伊福伸介、森本稔、斎本博之
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-07-13
    • Related Report
      2012 Final Research Report
  • [Book] Preparation, modification and application of chitin nanofibers in "Nanofibers: Synthesis, Preparations, and Application2012

    • Author(s)
      S. Ifuku
    • Publisher
      NOVA Publishers
    • Related Report
      2012 Final Research Report
  • [Book] Preparation, Modification and Application of Chitin Nanofibers in "Nanofibers: Synthesis, Preparations, and Applications"2012

    • Author(s)
      Shinsuke Ifuku
    • Total Pages
      16
    • Publisher
      NOVA Publishers
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://saimotolab.sakura.ne.jp/index.html

    • Related Report
      2012 Final Research Report
  • [Remarks] 斎本研究室

    • URL

      http://saimotolab.sakura.ne.jp/index.html

    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] キチンナノファイバーの製造方法、キチンナノファイバーを含む複合材料および塗料組成物、ならびにキトサンナノファイバーの製造方法、キトサンナノファイバーを含む複合材料および塗料組成物2013

    • Inventor(s)
      伊福伸介,斎本博之,矢野浩之,能木雅也,大村善彦
    • Industrial Property Rights Holder
      国立大学法人鳥取大学,国立大学法人京都大学,大村塗料株式会社
    • Acquisition Date
      2013-02-01
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 炎症性腸疾患治療剤2011

    • Inventor(s)
      伊福伸介, 斎本博之, 他
    • Industrial Property Rights Holder
      鳥取大学
    • Industrial Property Number
      2011-202193
    • Filing Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] ナノファイバー補強透明複合材2010

    • Inventor(s)
      伊福伸介, 斎本博之, 他
    • Industrial Property Rights Holder
      鳥取大学
    • Industrial Property Number
      2010-181572
    • Filing Date
      2010-08-16
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 繊維複合体及びその製造方法2010

    • Inventor(s)
      伊福伸介, 斎本博之, 他
    • Industrial Property Rights Holder
      鳥取大学
    • Industrial Property Number
      2010-181946
    • Filing Date
      2010-08-16
    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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