| Project/Area Number |
22550200
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Polymer/Textile materials
|
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| Research Institution | Kumamoto University |
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Principal Investigator |
SAKATA Masayo 熊本大学, 大学院・自然科学研究科, 准教授 (60187391)
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|---|
| Co-Investigator(Renkei-kenkyūsha) |
SASAKI Mitsuru 熊本大学, 大学院・自然科学研究科, 准教授 (40363519)
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 高分子微粒子 / エンドトキシン / LPS 吸着剤 / DNA 分離 / 包接作用 / 選択吸着 / シクロデキストリン / リポポリサッカライド / ＬＰＳ吸着剤 / ＤＮＡ分離 / キャビティ / DNA分離 / LPS吸着剤 / 包摂作用 |
|---|
| Research Abstract |
The copolymer particles for removal of lipopolysaccharide (LPS)were prepared by suspension copolymerization of -cyclodextrin (CyD) and1,6-hexamethylenediisocyanate. The copolymer (CyD content: 14-20 mol%) could selectivelyremoved LPS from a DNA solution (50 g/ml) containing LPS (15 EU/ml) at pH 6 and ionicstrength (u) of 0.05-0.2.
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