y -Cyclodextrin-polyurethane copolymer adsorbent for selective removalof endotoxin from DNA solution
Project/Area Number |
22550200
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Polymer/Textile materials
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Research Institution | Kumamoto University |
Principal Investigator |
SAKATA Masayo 熊本大学, 大学院・自然科学研究科, 准教授 (60187391)
|
Co-Investigator(Renkei-kenkyūsha) |
SASAKI Mitsuru 熊本大学, 大学院・自然科学研究科, 准教授 (40363519)
|
Project Period (FY) |
2010 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
Keywords | 高分子微粒子 / エンドトキシン / LPS 吸着剤 / DNA 分離 / 包接作用 / 選択吸着 / シクロデキストリン / リポポリサッカライド / LPS吸着剤 / DNA分離 / キャビティ / DNA分離 / LPS吸着剤 / 包摂作用 |
Research Abstract |
The copolymer particles for removal of lipopolysaccharide (LPS)were prepared by suspension copolymerization of -cyclodextrin (CyD) and1,6-hexamethylenediisocyanate. The copolymer (CyD content: 14-20 mol%) could selectivelyremoved LPS from a DNA solution (50 g/ml) containing LPS (15 EU/ml) at pH 6 and ionicstrength (u) of 0.05-0.2.
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Report
(4 results)
Research Products
(44 results)
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[Journal Article] Photochemicalengineering of graphene oxide nanosheets2012
Author(s)
M. Koinuma, C. Ogata, Y. Kamei, K.Hatakeyama, H. Tateishi, Y. Watanabe, T.Taniguchi, K. Gezuhara, S. Hayami, A.Funatsu, M. Sakata, Y. Kawahara, S.Kurihara, Y. Matsumoto
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Journal Title
Journal of Physical Chemistry C
Volume: Vol.116, No.37
Pages: 19822-19827
Related Report
Peer Reviewed
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