Sub-wavelength 3-dimentional imaging of biological tissue
| Project/Area Number |
22560032
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Applied optics/Quantum optical engineering
|
|---|
| Research Institution | University of Tsukuba |
|---|
Principal Investigator |
ITOH Masahide 筑波大学, 数理物質系, 教授 (30150874)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
YATAGAI Toyohiko 宇都宮大学, オプティックス教育研究センター, 教授 (90087445)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | 3次元計測 / 画像処理 / 生体計測 / ３次元計測 / 光学顕微鏡 / MTF / コヒーレンス / 微分干渉 / 光学的伝達関数 / デフォーカス / セクショニング / デフォーカス特性 / 訣像光学系 |
|---|
| Research Abstract |
We established the quantitative technique to visualize the shape and structure of biological tissue which has a small difference of a refractive index. We were able to get the sub-wavelength phase distribution as depth by using the phase modulation differential interference microscope which we developed. Moreover, when we observe three-dimensional object there was a problem which disturbs reconstruction with blurred image before and behind an exact image plane. Consequently, we combined the Nearest Neighbor Deblurring method with the phase reconstruction technique of a phase modulation differential interference microscope, and confirmed its availability.
|
Report
(4 results)
Research Products
(30 results)
