| Project/Area Number |
22560775
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biofunction/Bioprocess
|
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| Research Institution | Prefectural University of Hiroshima |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NISHIMOTO Jun 県立広島大学, 生命環境学部, 准教授 (80253582)
|
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| Co-Investigator(Renkei-kenkyūsha) |
UDA Taizo 大分大学, 工学部, 教授 (20232837)
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | インフルエンザ / ウイルス / 電解発光 / イムノリポソーム / 迅速判定 / ヘマグルチニン / 抗体 / ルテニウム錯体 / インフルエンザウイルス / 迅速検出 / リポソーム |
|---|
| Research Abstract |
Appearance of new influenza has threatened the life of human. In order to rapidly decide the infection, we researched novel method combining electrochemiluminescence (ECL) with a liposome, a small vesicle consisting of cell membrane. We have successfully enhanced the precision of the ECL data by optimizing the liposomepreparation and the detection procedure, and by preparing chemiluminescent rutheniumcomplexes encapsulated in the liposome. Consequently, we have detected the virus of hundreds of particles by 70-min measurement.
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