Activation mechanism of a bacterial two-componet system by an outer membrane lipoprotein sensing cell envelope stresses
Project/Area Number |
22570001
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Genetics/Genome dynamics
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Research Institution | Saitama University |
Principal Investigator |
HARA Hiroshi 埼玉大学, 大学院・理工学研究科, 准教授 (00173071)
|
Co-Investigator(Kenkyū-buntansha) |
MATSUMOTO Kouji 埼玉大学, 大学院・理工学研究科, 教授 (00119140)
MATSUOKA Satoshi 埼玉大学, 大学院・理工学研究科, 助教 (90509283)
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Project Period (FY) |
2010 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 外膜リポタンパク質 / 二成分制御系 / 細胞表層ストレス / 細菌リポタンパク質 / 機能ドメイン構造 / タンパク質間相互作用 |
Research Abstract |
The outer membrane lipoprotein RcsF is an essential component of the Rcs phosphorelay signal transduction system in Escherichia coli. It senses stresses imposed on the cell envelope and conveys the information to histidine kinase RcsC in the cytoplasmic membrane. It is suggested that RcsF functions as a ligand for RcsC in activating the system. RcsF has a region rich in proline and basic residues near the N terminus. This region is likely to play an important role in regulation of the function of RcsF in activating the Rcs system.
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Report
(4 results)
Research Products
(42 results)
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[Journal Article] Characterization of the Nuclear- and Plastid-Encoded secA-Homologous Genes in the Unicellular Red Alga Cyanidioschyzon merolae2011
Author(s)
Yosuke Koyama, Koji Takimoto, Asuka Kojima, Kei Asai, Satoshi Matsuoka, Toshiaki Mitsui, Kouji Matsumoto, Hiroshi Hara, Niji Ohta
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Journal Title
Bioscience, Biotechnology, and Biochemistry
Volume: 75
Issue: 10
Pages: 2073-2078
DOI
NAID
ISSN
0916-8451, 1347-6947
Related Report
Peer Reviewed
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[Presentation] 葉緑体Sec translocaseにおける2種のタンパク質膜透過駆動因子SecA ATPaseの機能2011
Author(s)
小山陽亮, 小嶋明日香, 小黒愛子, 坂本琴美, 滝元宏治, 松岡聡, 朝井計, 金子康子, 三ツ井敏明, 松本幸次, 原弘志, 太田に
Organizer
日本分子生物学会
Place of Presentation
パシフィコ横浜
Year and Date
2011-12-15
Related Report
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