Regulation in the dimerization of ribosome during sporulation inBacillus subtilis
Project/Area Number |
22570005
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Genetics/Genome dynamics
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Research Institution | Rikkyo University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 分子遺伝 / リボソーム / 枯草菌 / 胞子形成 / rRNA / rRNA分解 / ダイマーリボソーム / rRNAオペロン / 抗生物質耐性 |
Research Abstract |
We found that more than half of the 70S ribosome were inactivated and then dimerized by the hibernation promoting factor, Hpf (YvyD) in the early stage of sporulation. The rRNA of the dimer of 70S ribosome was attacked first and finally the dimer ribosome was degraded in the late stage of sporulation. The hpf gene is actively transcribed from the promoter which is recognized by 〓H at the onset of the sporulation.
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Report
(4 results)
Research Products
(84 results)
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[Journal Article] Single mutations introduced in the essential ribosomal protein L3 and S10 cause a sporulation defect in Bacillus subtilis.2013
Author(s)
Genki Akanuma, Shota Suzuki, Koichi Yano, Hideaki Nanamiya, Yousuke Natori, Namba Eri, Kazuya Watanabe, Kazumi Tagami, Takuya Takeda, Yuka Iizuka, Ako Kobayashi, Morio Ishizuka, Hirofumi Yoshikawa, and Fujio Kawamura.
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Journal Title
J. Gen. Appl. Microbiol.
Volume: 59
Pages: 106-117
NAID
Related Report
Peer Reviewed
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[Journal Article] Expression of a small (p)ppGpp synthetase, YwaC, in the (p)ppGpp0 mutant of Bacillus subtilis triggers YvyD-dependent dimerization of ribosome2012
Author(s)
Tagami K, Nanamiya H, Kazo Y, Maehashi M, Suzuki S, Namba E, Tozawa Y, Morimoto, T, Ogasawara N, Kageyama Y, Ara K, Ozaki K, Yoshida M, Kuroiwa H, Kuroiwa T, Ohashi Y, Kawamura F
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Journal Title
MicrobiologyOpen
Volume: (印刷中)
Issue: 2
Pages: 115-134
DOI
Related Report
Peer Reviewed
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