Interaction between Innate Immune Receptor CD14 and Ligand LPS on Membranes
Project/Area Number |
22570127
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Structural biochemistry
|
Research Institution | Suntory Foundation for Life Sciences |
Principal Investigator |
三浦 薫 (野村 薫 / 三浦 薫(野村薫)) 公益財団法人サントリー生命科学財団, 生物有機科学研究所, 研究員 (90353515)
|
Co-Investigator(Renkei-kenkyūsha) |
SHIMAMOTO Keiko 公益財団法人サントリー生命科学財団, 生物有機科学研究所, 主幹研究員 (70235638)
KUSUMOTO Shoichi 公益財団法人サントリー生命科学財団, 生物有機科学研究所, 所長 (30028253)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | GPIアンカー / 固体NMR法 / 脂質二重膜 / 自然免疫 / 酵母培養系 / GPIアンカー型蛋白質 / 固体NMR |
Research Abstract |
To complete the methodology, we changed the procedure into using a model membrane. We succeeded in obtaining high resolution solid-state NMR spectra of membrane samples in which pseudo GPI-anchored proteins were inserted
|
Report
(4 results)
Research Products
(20 results)