| Project/Area Number |
22570161
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biophysics
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| Research Institution | Osaka University |
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Principal Investigator |
MINAMINO Tohru 大阪大学, 生命機能研究科, 准教授 (20402993)
|
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| Research Collaborator |
KINOSHITA Miki 大阪大学, 生命機能研究科, 特任研究員
MORIMOTO Yusuke 大阪大学, 生命機能研究科, 特任研究員
HARA Noritaka 大阪大学, 生命機能研究科, 大学院生
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
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| Keywords | 電子顕微鏡 / 分子モーター / 遺伝学 / 細菌 / 蛋白質 |
|---|
| Research Abstract |
The bacterial flagellar ATPase complexes, which consist of FliH, FliI and FliJ, associate with the docking platform of the export gate through an interaction between FliH and an export gate protein FlhA, thereby forming the FliI6-FliJ ring complex. A specific interaction of FliJ with FlhA brought about by the FliHX-FliI_6 complex allows the export gate to fully utilize proton motive force across the cytoplasmic membrane to drive flagellar protein export.
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