Do HOX genes in the visceral mesoderm control regional differentiationof the endoderm?
| Project/Area Number |
22570205
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | Yamaguchi University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HARADA Yumiko 山口大学, 大学院・理工学研究科, 助教 (70284239)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 器官形成 / ショウジョウバエ / 中腸 / HOX / 内胚葉 / 内臓筋 / 部域分化 / HOX遺伝子 / Dpp |
|---|
| Research Abstract |
This research project was undertaken in order to elucidate roles of HOX genes in the visceral mesoderm of Drosophila midgut. During the research period
epithelial genes suitable as specific markers for regional differentiation of the midgut were identified
and phenotypes of the mutants and misexpression of HOX genes were analyzed.
It was demonstrated that roles of HOX genes in the visceral mesoderm are induction and regulation of regional differentiation of the underlying endoderm.
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Report
(4 results)
Research Products
(20 results)
