Evolution of genetic regulatory networks through amplification and transposition of transposons
Project/Area Number |
22570212
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Evolutionary biology
|
Research Institution | Hiroshima University |
Principal Investigator |
HIKOSAKA Akira 広島大学, 大学院・総合科学研究科, 助教 (30263635)
|
Co-Investigator(Kenkyū-buntansha) |
KAWAHARA Akira 広島大学, 大学院・総合科学研究科, 教授 (50112157)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | 遺伝子進化 / トランスポゾン / ツメガエル / ゲノム進化 / MITE / 自然選択 / 遺伝子発現調節 / 進化 / ゲノム / 遺伝子発現 |
Research Abstract |
We studied the possibility that some transposons whose transposition activities have been retained for a long time in Xenopushave been involved in the evolution of genetic regulatory network. We developed a new strategy to find and classify the T2-MITE transposon family and searched the Xenoousgenomes for T2-MITEs. In addition, we analyzed insertion loci of such transposons and gene expression patterns of neighbor genes and found T2-MITE subfamilies whose transposition and amplification might have driven the evolution of genetic regulatory network of Xenopus.
|
Report
(4 results)
Research Products
(13 results)