| Project/Area Number |
22580094
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Kanazawa Institute of Technology |
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Principal Investigator |
ODA Shinobu 金沢工業大学, バイオ・化学部, 教授 (00503963)
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| Co-Investigator(Kenkyū-buntansha) |
HORIBE Hideo 金沢工業大学, バイオ・化学部, 教授 (00372243)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 糸状菌 / 界面 / マイクロスフェアー / 発酵 / 微生物変換 / 微生物機能 / 界面バイオリアクター / 界面発酵法 / 糸状菌細胞 / 中空微粒子 / イオン交換性微粒子 / 疎水性微粒子 |
|---|
| Research Abstract |
In an extractive liquid-surface immobilization system and aliquid-liquid interface bioreactor, the effects of ion-exchange and hydrophobic resin micro-particles on morphological, physiological, and biochemical properties of fungal cells locatedon an aqueous-organic interface were investigated. While the addition of cation-exchangeand chelating resin microparticles into a ballooned polyacrilonitrile microsphere layerstrongly inhibited the fungal growth, fermentation and hydroxylation activities, theaddition of anion-exchange resin microparticles significantly increased growth, fermenta-tion and hydroxylation activities and decreased of spore formation. Furthermore, theaddition of hydrophobic resin microparticles also increased alkane-hydroxylation activity.
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