Stress response resulting in genetic diversity by transposable elements in Aspergillus oryzae
| Project/Area Number |
22580096
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | 秋田県総合食品研究センター |
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Principal Investigator |
OGASAWARA Hironobu 秋田県総合食品研究センター, 醸造試験場, 上席研究員 (50390901)
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| Co-Investigator(Kenkyū-buntansha) |
TAKAHASHI Saori 秋田県総合食品研究センター, 食品加工研究所, 所長 (10142184)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 遺伝子発現 / mRNA / トランスポゾン / 麹菌 / 多様性 / 外来性遺伝子 |
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| Research Abstract |
In the survey using a stress-fluctuation cDNA browser afforded by high-throughput sequencing, several kinds of transposon-like elements were preferentially discovered in novel active transcriptional regions. Almost of the elements were inactivated by cryptic splicing which was inhibited by extreme stress. An intensity of mature polyadenylation to the mRNA of a novel DNA transposon AoTanl increased under stress conditions. It was suggested that mature and active mRNA molecules of transposon-like elements tended to be increased during the extreme stress, resulting in genetic diversity by transposable elements in Aspergillus oryzae.
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Report
(4 results)
Research Products
(29 results)
