Selective control of plant P450 enzymes: Development of small molecules regulating plant growth and production of sweet substances
Project/Area Number |
22580118
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Bioproduction chemistry/Bioorganic chemistry
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Research Institution | Shizuoka University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
OHNISHI Toshiyuki 静岡大学, 若手グローバル研究リーダー育成拠点, 特任助教 (60542165)
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Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 植物成長調節物質 / シトクロムP450酵素 / 阻害剤 / ジベレリン / アブシジン酸 / 乾燥耐性 / 植物P450 / ジベレリン生合成 / 甘味物質 / アゾール化合物 |
Research Abstract |
This study has developed the three-types of selective inhibitors of cytochrome P450 enzymes involved in biosynthesis of gibberellin that promotes seed germination and stem elongation, catabolic inactivation of abscisic acid that antagonizes gibberellin-promoted seed germination and plays an essential role in adaptive stress responses, and biosynthesis of stevioside, a sweet substance of Stevia. These inhibitors are expected to be a useful tool to control plant growth and production of sweet substances.
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Report
(4 results)
Research Products
(17 results)
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[Journal Article] Abscinazole-E1, a novel chemical tool for exploring the role of ABA 8'-hydroxylase CYP707A2011
Author(s)
Okazaki, M.; Nimitkeatkai, H.; Muramatsu, T.; Aoyama, H.; Ueno, K.; Mizutani, M.; Hirai, N.; Kondo, S.; Ohnishi, T.; Todoroki, Y.
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Journal Title
Bioorg. Med. Chem
Volume: 19
Issue: 1
Pages: 406-413
DOI
NAID
Related Report
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