Polyphenols of functional foods as materialseffectiveon tumor cells
| Project/Area Number |
22580128
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Okayama University |
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Principal Investigator |
HATANO Tsutomu 岡山大学, 大学院・医歯薬学総合研究科, 教授 (50127578)
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| Co-Investigator(Kenkyū-buntansha) |
TAKEUCHI Yasuo 岡山大学, 大学院・医歯薬学総合研究科, 教授 (00163387)
SAKAGAMI Hiroshi 明海大学, 歯学部, 教授 (50138484)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 機能性食品 / ポリフェノール / タンニン / 抗腫瘍作用 / 植物組織培養 / 人工タンニン / ギョリュウ科 / バラ科 / 食品 / 植物 / 機能性成分 / 培養がん細胞 / 口腔がん / ギョリュウ科植物 / 未利用植物資源 / 高分子ポリフェノール / 物質生産 / 口腔がん細胞 |
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| Research Abstract |
Tannins of several plant resources including those used for functional foods were investigated, and various tannins including new ones were isolated from a tamaricaceous plant grown in Egypt. Several tannins among them showed selective cytotoxicity against human oral squamous cell carcinoma (OSCC) cell lines. Those tannins were produced in cultured tissues induced from Tamarix tetrandra successfully. Artificial tannins based on oligosaccharide cores were newly synthesized, and they also showed selective cytotoxicity against OSCC cell lines.
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Report
(4 results)
Research Products
(18 results)
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[Book] A Compendium of Essays on Alternative Therapy (edited by Bhattacharya A) (Chapter 13, Functional Analysis of Natural Polyphenols and Saponins as Alternative Medicines)2012
Author(s)
Sakagami H, Kushida T, Makino T, Hatano T, Shirataki Y, Matsuta T, Matsuo Y, Mimaki Y, In Tech (Rijeka, Croatia)
Related Report
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