| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Research Abstract |
Hop (Humulus lupulus L.) pomace contains procyanidin-rich polyphenols, large oligomeric compounds of catechin. Effect of high dose (1%) of dietary hop pomace polyphenols (HP) in OLETF rats, an animal model of type 2 diabetes, was studied. The rats fed HP tended to have a lower body weight and reduced white adipose tissue weight than the rats fed a control diet. Triglyceride levels in both plasma and liver tended to be lower in the HP fed group than in the control group. Thus, dietary HP may exert anti-obesity effect through the ameliorative function on hepatic fatty acid metabolism and inhibition of fat and glucose absorption from intestine.
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