Production of recombinant Japanese eel gonadotropins and their roles on the oogenesis
| Project/Area Number |
22580219
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
General fisheries
|
|---|
| Research Institution | Fisheries Research Agency |
|---|
Principal Investigator |
KAZETO Yukinori 独立行政法人水産総合研究センター, 増養殖研究所・養殖技術部, 主任研究員 (60399996)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
GEN Koichiro 水産総合研究センター, 西海区水産研究所, 主任研究員 (80372051)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | 水産学 / ウナギ / 生殖生理 / バイオテクノロジー |
|---|
| Research Abstract |
Two recombinant eel gonadotropins (rGTH: rFSH-CTP and rLH-CTP) with long-lasting life were produced in mammalian cells. Administration of these rGTH could induce maturation of immature female eel. Furthermore, ovarian mass and expression of genes related to reproduction, induced by rFSH-CTP were significantly different from those by rLH-CTP, which indicates that two rGTH differentially act in the ovary of eel.
|
Report
(4 results)
Research Products
(5 results)
