Critical role of hypothalamic dopamine in regulation of food intake by growing chickens on lysine-free diet
| Project/Area Number |
22580304
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Utsunomiya University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 栄養・飼養 / 摂食量 / 視床下部 / モノアミン / 脳微小透析法 / リジン欠乏 / ドーパミン / 鶏ヒナ / 血漿アミノ酸濃度 / food intake / hypothalamus / monoamines / brain microdyalysis / chicken / brain microdialysis |
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| Research Abstract |
1.Central perfusion of L-DOPA as well as peripheral administration of lysine kept the extracellularDA level in the VMH at baseline of chickens fed on a lysine-free diet.
2. Keeping the extracellular DA level in the VMH prevents chickens on the lysine-free diet prevented from decreasing their voluntary food intake.
3. DA in the VMH plays a critical role in food intake regulation in chickens fed on a lysine-free diet.
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Report
(4 results)
Research Products
(24 results)
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[Presentation] 日本家禽学会2012年春季大会(名古屋)2012
Author(s)
Mohammad Rashedul Alam, FumiakiYoshizawa and Kunio Sugahara
Organizer
Oral administration of lysine resotres food intake and ventromedial hypothalamic dopamine in chickens on a lysine-free diet
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