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Alcohol metabolism and its potential role of causing fatty liver in ruminants

Research Project

Project/Area Number 22580310
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Zootechnical science/Grassland science
Research InstitutionHiroshima University

Principal Investigator

TANIGUCHI Kohzo  広島大学, 大学院・生物圏科学研究科, 教授 (30093777)

Co-Investigator(Kenkyū-buntansha) OBITSU Taketo  広島大学, 生物圏科学研究科, 准教授 (30194632)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords反芻家畜 / 脂肪肝 / エタノール / 肝臓 / 脂質代謝 / 反芻動物 / 畜産学 / 栄養学 / 生理学 / 脂質
Research Abstract

Effects of alcohol consumption on carbohydrate and lipid metabolism in ruminants were investigated by determining the changes of plasma concentrations and net fluxes by splanchnic tissues of metabolites with ruminal ethanol infusion in sheep. Ruminal ethanol infusion decreased plasma glucose concentration, increased plasma triglyceride concentration and net hepatic release of triglyceride in sheep. These results indicate that ethanol has a potential role of facilitatinghepatic lipid synthesis in ruminants.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (12 results)

All 2013 2012 2011 Other

All Presentation (11 results) Remarks (1 results)

  • [Presentation] Effects of ethanol and feeding levels on splanchnic nutrient metabolism in sheep2013

    • Author(s)
      Obitsu T, Nishimura K, Udaka Y, Sugino T, Taniguchi K
    • Organizer
      ISEP
    • Place of Presentation
      California, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Effects of ethanol on splanchnic nutrient metabolism in sheep at different intake levels2013

    • Author(s)
      Obitsu T, Nishimura K, Udaka Y, Sugino T, Taniguchi K
    • Organizer
      4th International Symposium on Energy and Protein Metabolism and Nutrition
    • Place of Presentation
      Sacramento, CA. USA.
    • Related Report
      2012 Annual Research Report
  • [Presentation] 栄養水準の違いがヒツジのアルコール代謝に及ぼす影響2012

    • Author(s)
      小櫃剛人,西村加奈子,宇高優美,杉野利久.谷口幸三
    • Organizer
      第62回関西畜産学会
    • Place of Presentation
      和歌山
    • Year and Date
      2012-09-14
    • Related Report
      2012 Final Research Report
  • [Presentation] ヒツジの消化管組織におけるインスリン・グルカゴン流量に及ぼすエタノール注入の影響2012

    • Author(s)
      杉野利久,宇高優美,西村加奈子,福森理加,小櫃剛人,谷口幸三
    • Organizer
      日本畜産学会第115回大会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] ヒツジの消化器官組織におけるインスリン・グルカゴン流量に及ぼすエタノール注入の影響2012

    • Author(s)
      杉野利久・宇高優美・西村加奈子・福森理加・小櫃剛人・谷口幸三
    • Organizer
      第115回日本畜産学会
    • Place of Presentation
      名古屋市
    • Year and Date
      2012-03-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒツジの第一胃内へのエタノール注入が血漿中の酵素活性と代謝物濃度に及ぼす影響2011

    • Author(s)
      西村加奈子,宇高優美,小櫃剛人,谷口幸三,杉野利久
    • Organizer
      第61回関西畜産学会
    • Place of Presentation
      岡山
    • Year and Date
      2011-09-13
    • Related Report
      2012 Final Research Report
  • [Presentation] 第一胃内アルコール投与がヒツジのインスリン感受性に及ぼす影響2011

    • Author(s)
      宇高優美,西村加奈子,福森理加,杉野利久,小櫃剛人,谷口幸三
    • Organizer
      第61回関西畜産学会
    • Place of Presentation
      岡山
    • Year and Date
      2011-09-13
    • Related Report
      2012 Final Research Report
  • [Presentation] ヒツジの第一胃内へのエタノール注入が血漿中の酵素活性と代謝物濃度に及ぼす影響2011

    • Author(s)
      西村加奈子・宇高優美・小櫃剛人・谷口幸三・杉野利久
    • Organizer
      第61回関西畜産学会
    • Place of Presentation
      岡山市
    • Year and Date
      2011-09-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] 第一胃内アルコール投与がヒツジのインスリン感受性に及ぼす影響2011

    • Author(s)
      宇高優美・西村加奈子・福森理加・杉野利久・小櫃剛人・谷口幸三
    • Organizer
      第61回関西畜産学会
    • Place of Presentation
      岡山市
    • Year and Date
      2011-09-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒツジの第一胃内へのエタノール注入が血漿中の酵素活性と代謝物濃度に及ぼす影響2011

    • Author(s)
      西村加奈子・宇高優美・小櫃剛人・谷口幸三・杉野利久
    • Organizer
      関西畜産学会
    • Place of Presentation
      岡山大学
    • Year and Date
      2011-09-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] 栄養水準の違いがヒツジのアルコール代謝に及ぼす影響

    • Author(s)
      小櫃剛人,西村加奈子,宇高優美,杉野利久,谷口幸三
    • Organizer
      関西畜産学会第62回大会
    • Place of Presentation
      和歌山市
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://home.hiroshima-u.ac.jp/shiyou/index.shtml

    • Related Report
      2012 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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