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Development of Functional Fermented Meat Products

Research Project

Project/Area Number 22580311
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Zootechnical science/Grassland science
Research InstitutionUniversity of Miyazaki

Principal Investigator

MUGURUMA Michio  宮崎大学, 産学・地域連携センター, 研究員 (50091369)

Co-Investigator(Kenkyū-buntansha) KAWAHARA Satoshi  宮崎大学, 農学部, 准教授 (30284821)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords食肉 / 発酵 / 乳酸菌 / 機能性 / 血圧上昇抑制 / 抗酸化活性 / 嗜好性 / 血圧上昇制
Research Abstract

We screened suitable lactic acid bacteria (LAB) strains for use in functional fermented meat products by analyzing European fermented sausages with 60 probiotic LAB strains. Lactobacillus (L) sakei strain No. 23 and L. curvatus strain No.28 were selected because of their effects on pH, lactic acid production and degradation of myosin B after fermentation of meat protein. They were salt and nitrite-resistant strains which are indispensable for manufacture of meat products. Then, we prepared fermented sausages by utilizing L. sakei strain No. 23 or L. curvatus strain No.28. Analyses of fermented sausages revealed that lactic acid numbers increased and production of coliform bacillus repressed. SDS-PAGE results suggest that meat protein in fermented sausages has been hydrolyzed. Many bioactive peptides and amino acids were generated from fermented sausages. These fermented sausages showed the high antioxidant and antihypertensive activity, and acceptable sensory quality characteristic.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (32 results)

All 2013 2012 2011 2010

All Journal Article (17 results) (of which Peer Reviewed: 14 results) Presentation (9 results) Book (3 results) Patent(Industrial Property Rights) (3 results) (of which Overseas: 1 results)

  • [Journal Article] ブタ肝臓水解物の成分分析と抗酸化活性およびアンギオテンシン変換酵素(ACE)阻害活性の検討2013

    • Author(s)
      井上尚典、浜崎敦子、日高修二、三浦直良、深堀勝博、丸山眞杉、河原 聡、太田良一、六車 三治男
    • Journal Title

      薬学雑誌

      Volume: 133(1) Pages: 107-115

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] メタボリックシンドロームモデルラット(SHR/NDmcr-cp)における肝臓水解物の血糖に及ぼす影響2013

    • Author(s)
      井上尚典、日高修二、三浦直良、山田 耕太郎、深堀勝博、丸山眞杉、河原 聡、太田良一、六車 三治男
    • Journal Title

      薬学雑誌

      Volume: 133(1) Pages: 177-123

    • NAID

      130003361893

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Application of probiotis from Mongolian dairy products to fermented dairy products and its effects on human defection.2013

    • Author(s)
      S. Takeda, R. Fujimoto, S. Takenoyama, M. Takeshita, Y. Kikuchi, C. Tsend-Ayush, B. Dashnyam, M. Muguruma, S. Kawahara
    • Journal Title

      Food Sci. Technol. Res.

      Volume: 19(2) Pages: 245-253

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ブタ肝臓水解物の成分分析と抗酸化活性及びアンギオテンシン変換酵素(ACE)阻害活性2013

    • Author(s)
      井上尚典・浜崎敦子・日高修二・三浦直良・深堀勝博・丸山眞杉・河原 聡・太田一良・六車 三治男
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 133 Pages: 107-115

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] メタボリックシンドロームラット(SHR/NDmcr-cp)における肝臓水解物の血糖に及ぼす影響2013

    • Author(s)
      井上尚典・日高修二・三浦直良・山田 耕太郎・深堀勝博・丸山眞杉・河原 聡・太田一良・六車 三治男
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 133 Pages: 117-123

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A combination of soybean and skimmed milk reduces osteoporosis in rats.2012

    • Author(s)
      M. Muguruma, A.M. Ahhmed, S. Kawahara, K. Kusumegi, T. Hishinuma, K. Ohya, T. Nakamura.
    • Journal Title

      J. Funct. Foods

      Volume: 4(4) Pages: 810-818

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A combination of soybean and skimmed milk reduces osteoporosis in rats.2012

    • Author(s)
      Michio Muguruma, Abdulatef Mrghni Ahhmed, Satoshi Kawahara, Kazuhiro Kusumegi, Tsuyoshi Hishimuma, Keiichi Ohya, Toyoo Nakamura
    • Journal Title

      Journal of Functional Foods

      Volume: 4 Issue: 4 Pages: 810-818

    • DOI

      10.1016/j.jff.2012.05.009

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 食肉由来機能性成分の畜種別差異の比較検討についての研究 (III)2012

    • Author(s)
      六車 三治男・久保田 大樹・河原 聡
    • Journal Title

      食肉に関する助成研究調査報告書、(財)伊藤記念財団

      Volume: 30 Pages: 7-18

    • Related Report
      2012 Annual Research Report
  • [Journal Article] The investigation of probiotic acid bacteria isolated from traditional Mongolian dairy products.2011

    • Author(s)
      S. Takeda, Y. Yamasaki, M. Takeshita, Y. Kikuchi, C. Tsend-Ayush, B. Dashnyam, A.M. Ahhmed, S. Kawahara, M. Muguruma
    • Journal Title

      Anim. Sci. J.

      Volume: 82(4) Pages: 571-579

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of oral administration of heat-killed probiotics from Mongolian daily products against influenza infection in mice: Alleviation of influenza infection by its immunomodulatory activity through intestinal immunity.2011

    • Author(s)
      S. Takeda, M. Takeshita, Y. Kikuchi, B. Dashnyam, S. Kawahara, H. Yoshida, W. Watanabe, M. Muguruma, M. Kurokawa
    • Journal Title

      Inter. Immunophamacol.

      Volume: 11 Pages: 1979-1983

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of oral administration of heat-killed probiotics from Mongolian dairy products against influenza infection in mice : Alleviation of influenza infection by its immunomodulatory activity through intestinal immunity2011

    • Author(s)
      S.Takeda, M.Takeshita, Y.Kikuchi, B.Dashnyam, S.Kawahara, H.Yoshida, W.Watanabe, M.Muguruma, M.Kurokawa
    • Journal Title

      International Immunophamacology

      Volume: 11 Pages: 1976-1983

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The investigation of probiotic potential of lactic acid bacteria isolated from traditional Mongolian dairy products2011

    • Author(s)
      S.Takeda, Y.Yamasaki, M.Takeshita, Y.Kikuchi, C.Tsend-Ayush, B.Dashnyam, A.M.Ahhmed, S.Kawahara, M.Muguruma
    • Journal Title

      Animal Science Journal

      Volume: 82 Pages: 571-576

    • NAID

      10030377843

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 食肉由来機能性成分の畜種別差異の比較検討についてII2011

    • Author(s)
      久保田大樹, 河原聡, 六車三治男
    • Journal Title

      食肉に関する助成研究調査報告書

      Volume: 29 Pages: 29-39

    • Related Report
      2011 Annual Research Report
  • [Journal Article] A review of meat protein hydrolysates and hypertention.2010

    • Author(s)
      A.M. Ahhmed, M. Muguruma
    • Journal Title

      Meat Sci.

      Volume: 86(1) Pages: 110-118

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of osmotic dehydration sheets on freshness parameters of thunnus thynnus stored at cold temperatures.2010

    • Author(s)
      K. Saito, N. Hamada-Sato, A.M. Ahhmed, S. Kawahara, M. Muguruma
    • Journal Title

      J. Food Process. Preserv

      Volume: 34(6) Pages: 1103-1120

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A review of meat protein hydrolysates and hypertension2010

    • Author(s)
      Abdulatef Mrghni Ahhmed, Michio Muguruma
    • Journal Title

      Meat Science

      Volume: 86 Pages: 110-118

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 食肉由来機能性成分の畜種別差異の比較検討について2010

    • Author(s)
      久保田大樹・アブドラティフ・アーメド・河原聡・六車三治男
    • Journal Title

      食肉に関する助成研究調査報告書

      Volume: 28 Pages: 1-9

    • Related Report
      2010 Annual Research Report
  • [Presentation] 嗜好性に富む高機能発酵食肉製品製造の試み2013

    • Author(s)
      六車 三治男 竹田志郎、竹之山 愼一、河原 聡、中出浩二、沼田正寛、小齊喜一
    • Organizer
      第116回日本畜産学会大会
    • Place of Presentation
      安田女子大学、広島市
    • Year and Date
      2013-03-30
    • Related Report
      2012 Final Research Report
  • [Presentation] 嗜好性に富む高機能発酵食肉製品製造の試み2013

    • Author(s)
      六車 三治男・竹田志郎・竹之山 愼一・河原 聡・中出浩二・沼田正寛・小齊喜一
    • Organizer
      第116回日本畜産学会大会
    • Place of Presentation
      安田女子大学(広島市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 高機能発酵食肉製の製造に関する研究2011

    • Author(s)
      松藤 久、秋吉亮佑、竹田志郎、河原 聡、六車 三治男
    • Organizer
      日本農芸化学会西日本支部・中四国支部合同大会
    • Place of Presentation
      宮崎大学
    • Year and Date
      2011-09-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 高機能発酵食肉製品の製造に関する研究2011

    • Author(s)
      松藤久, 秋吉亮佑, 竹田志郎, 河原聡, 六車三治男
    • Organizer
      日本農芸化学会西日本支部・中四国支部合同大会
    • Place of Presentation
      宮崎大学
    • Year and Date
      2011-09-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高機能発酵食肉製品製造のための乳酸菌の選別2011

    • Author(s)
      久保田大樹, 河原聡, 六車三治男
    • Organizer
      日本農芸化学会西日本支部・中四国支部合同大会
    • Place of Presentation
      宮崎大学
    • Year and Date
      2011-09-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高機能発酵食肉製品製造のための乳酸菌の選別2011

    • Author(s)
      松藤 久、秋吉亮佑、竹田志郎、河原 聡、六車 三治男
    • Organizer
      第114回日本畜産学会大会
    • Place of Presentation
      北里大学十和田キャンパス
    • Year and Date
      2011-08-26
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] アミノ酸および食肉タンパク質酵素分解物の抗酸化活性機序2011

    • Author(s)
      久保田 大樹、河原 聡、六車 三治男
    • Organizer
      第114回日本畜産学会大会
    • Place of Presentation
      北里大学十和田キャンパス
    • Year and Date
      2011-08-26
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] A review of meat protein hydrolysates and hypertention.2010

    • Author(s)
      M. Muguruma
    • Organizer
      56th International Congress of Meat Science and Technology
    • Place of Presentation
      Jeju, South Korea
    • Year and Date
      2010-08-20
    • Related Report
      2012 Final Research Report
  • [Presentation] A review of meat protein hydrolysates and hypertension.2010

    • Author(s)
      M.Muguruma
    • Organizer
      56^<th> International Congress of Meat Science and Technology.
    • Place of Presentation
      Jeju, South Korea
    • Year and Date
      2010-08-20
    • Related Report
      2010 Annual Research Report
  • [Book] 新しい食品加工学(食品の保存・加工・流通と栄養)2011

    • Author(s)
      六車 三治男
    • Total Pages
      212
    • Publisher
      南江堂
    • Related Report
      2012 Final Research Report
  • [Book] 新しい食品加工学-食品の保存・加工・流通と栄養-2011

    • Author(s)
      六車三治男 (分担執筆)
    • Publisher
      南江堂
    • Related Report
      2010 Annual Research Report
  • [Book] 食肉用語事典(新改訂版)2010

    • Author(s)
      六車 三治男
    • Total Pages
      532
    • Publisher
      食肉通信社
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 高純度ヘパリンおよびその製造方法2011

    • Inventor(s)
      六車 三治男、村田浩二
    • Industrial Property Rights Holder
      六車 三治男、村田浩二
    • Filing Date
      2011-12-13
    • Related Report
      2012 Final Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 高純度ヘパリンおよびその製造方法2010

    • Inventor(s)
      六車 三治男、村田浩二
    • Industrial Property Rights Holder
      六車 三治男、村田浩二
    • Industrial Property Number
      2010-205310
    • Filing Date
      2010-09-14
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] アンギオテンシン変換酵素阻害ペプチド2010

    • Inventor(s)
      片山員典、府中英孝、杉山雅治、六車 三治男
    • Industrial Property Rights Holder
      片山員典、府中英孝、杉山雅治、六車 三治男
    • Acquisition Date
      2010-03-10
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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