Alteration of number and type of myofiber of offspring by maternal nutritional regulation and postnatal thyroid manipulation
Project/Area Number |
22580315
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Zootechnical science/Grassland science
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Research Institution | National Agriculture and Food Research Organization |
Principal Investigator |
KATSUMATA Masaya 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所家畜生理栄養研究領域, 上席研究員 (60355683)
|
Co-Investigator(Renkei-kenkyūsha) |
ISHIDA Aiko 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所家畜生理栄養研究領域, 研究員 (30414684)
ASHIHARA Akane 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所家畜生理栄養研究領域, 研究員 (40547717)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Keywords | 栄養・飼養 / ブタ / 筋形成 / アミノ酸 / 甲状腺ホルモン / 筋線維 / 栄養学 / 胎児 |
Research Abstract |
Pregnant sows were fed a diet supplemented with arginine and glycine from day 25 to day 50 of the parturition. The piglets of the sows were orally given either thyroid hormone (T4) or an anti-thyroid agent (PTU) for 3 weeks from 1 day old. The supplementation of arginine and glycine to the maternal diet affected myosin heavy chain gene expression in longissimus dorsi muscle of the 1-day-old piglets. Further, we obtained evidence that thyroid hormone controlled ratio of type I myofiber of longissimus dorsi muscle in the pig during postnatal development.
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Report
(4 results)
Research Products
(2 results)