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Elucidation of the molecular mechanisms controlling the differentiation of the vomeronasal system during ontogeny

Research Project

Project/Area Number 22580329
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Basic veterinary science/Basic zootechnical science
Research InstitutionIwate University

Principal Investigator

TANIGUCHI Kazuyuki  岩手大学, 農学部, 教授 (70148089)

Co-Investigator(Kenkyū-buntansha) OMOE Katsuhiko  岩手大学, 農学部, 教授 (60224309)
NAKAMUTA Nobuaki  岩手大学, 農学部, 准教授 (00305822)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords鋤鼻器 / フェロモン / 発生 / マイクロアレイ / 発生・分化 / 解剖学 / 獣医学
Research Abstract

The vomeronasal organ (VNO) is one of the olfactory organs in vertebrates and constituting the pheromone detecting system. In this study, we analyzed the molecular mechanisms controlling the differentiation and development of the VNO during ontogeny. We revealed the change of the gene expression by DNA microarray analysis, and the localization of cells expressing the genes by in situ hybridization and immunohistochemistry. We obtained useful findings about the functional division between the olfactory epithelium, constituting the general olfactory system, and the VNO, constituting the pheromone detecting system.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (9 results)

All 2013 2012 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (6 results)

  • [Journal Article] Analysis of Glycoproteins Produced by the Associated Gland in the Olfactory Organ of Lungfish2013

    • Author(s)
      Nakamuta, N., Nakamuta, S., Taniguchi, K. and Taniguchi, K.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 75 Issue: 7 Pages: 887-893

    • DOI

      10.1292/jvms.12-0547

    • NAID

      130003362152

    • ISSN
      0916-7250, 1347-7439
    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Localization of the primordial vomeronasal organ and its relationship to the associated gland in lungfish2013

    • Author(s)
      Nakamuta, S., Nakamuta, N., Taniguchi, K. and Taniguchi, K.
    • Journal Title

      J. Anat

      Volume: 222 Issue: 4 Pages: 481-485

    • DOI

      10.1111/joa.12025

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histological and ultrastructural characteristics of the primordial vomeronasal organ in lungfish2012

    • Author(s)
      Nakamuta, S., Nakamuta, N., Taniguchi, K. and Taniguchi, K.
    • Journal Title

      Anat. Rec

      Volume: 295 Issue: 3 Pages: 481-491

    • DOI

      10.1002/ar.22415

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] Expression of aquaporin 3 in the progenitor cells of vomeronasal receptor cells2012

    • Author(s)
      Nakamuta, N., Kashihara, A., Okita, T., Shimizu, M. and Taniguchi, K.
    • Organizer
      The 4th Congress of Asian Association of Veterinary Anatomists
    • Place of Presentation
      Phuket Graceland Resort & Spa, Thailand
    • Year and Date
      2012-10-25
    • Related Report
      2012 Final Research Report
  • [Presentation] Morphological study on the glandular epithelium associated with the primordial vomeronasal organ in the lungfish2012

    • Author(s)
      Nakamuta, S., Nakamuta, N., Taniguchi, K. and Taniguchi, K.
    • Organizer
      AChemS XXXIV Annual Meeting
    • Place of Presentation
      Hyatt Huntington Beach, CA, U.S.A.
    • Year and Date
      2012-04-26
    • Related Report
      2012 Final Research Report
  • [Presentation] ラットの嗅覚器におけるアクアポリン発現の免疫組織化学的解析2012

    • Author(s)
      沖田敏朗、柏原 篤、中牟田信明、谷口和之
    • Organizer
      第153回日本獣医学会学術集会
    • Place of Presentation
      大宮ソニックシティ、大宮
    • Year and Date
      2012-03-28
    • Related Report
      2012 Final Research Report
  • [Presentation] 化学感覚としての嗅覚2012

    • Author(s)
      谷口和之
    • Organizer
      日本獣医師会獣医学術学会年次大会
    • Place of Presentation
      札幌コンベンションセンター(北海道)(招待講演)
    • Year and Date
      2012-02-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] p53ファミリーと嗅覚器の発生について2012

    • Author(s)
      中牟田信明
    • Organizer
      日本獣医師会獣医学術学会年次大会
    • Place of Presentation
      札幌コンベンションセンター(北海道)(招待講演)
    • Year and Date
      2012-02-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] Expression of aquaporin 3 in the progenitor cells of vomeronasal receptor cells.

    • Author(s)
      Nakamuta, N., Kashihara, A., Okita, T., Shimizu, M. and Taniguchi, K.
    • Organizer
      The 4th Congress of Asian Association of Veterinary Anatomists.
    • Place of Presentation
      Phuket Graceland Resort & Spa
    • Related Report
      2012 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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