Evaluation of Implantation of Autologous In Vivo Tissue-Engineered Valved after Valve Transplantation
| Project/Area Number |
22580369
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Clinical veterinary science
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| Research Institution | Nihon University |
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Principal Investigator |
UECHI Masami 日本大学, 生物資源科学部, 教授 (90296426)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 生体再生 / 肺動脈弁 / 心臓外科手術 / 先天性心臓病 / 血液循環 / 再生医療 / 人工弁 / 弁移植 |
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| Research Abstract |
We developed completely autologous valved eonduits in vivo tissue engineering, whichhad appropriate compliance and robustness. Postoperative echcardiographydemonstrated smooth movement of the leaflets with little regurgitation for at least upto 3 months. Good functioning as the pulmonary valve was observed after implantation of firstly developed autologous valved conduits with completely autologous tissues,which will become a valid future option in adolescents
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Report
(4 results)
Research Products
(14 results)
