| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
Inhaled- steroid bring the great advance in the therapy of athma. However, as for an elderly's asthma, the impairment of a respiratory-epithelium cells and its structural change break out refractory cases from a severe airway inflammation and remodeling. So, in this study, we analyzed the therapeutic potential of the novel curcumin derivative and the endogenous ligand of the alpha7 subunit of nicotinic acetylcholine receptors, and clarified its effectiveness in airway inflammation and remodeling.
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