| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
The effect of nano-sized zinc oxide and titanium oxide on autoimmune diseases was investigated. Collagen-induced arthritis (CIA) in mice was used as a model of autoimmune diseases and various doses of these nanomaterials were administered. As a result, both nano-sized materials failed to influence CIA. However, the materials appeared to increase the production of Th2 cytokines, suggesting that they might affect Th2-dependent allergic diseases.
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