Reversal of multidrug resistance by dual inhibitor of anticancer drug efflux transporter and transcription factor.
| Project/Area Number |
22590151
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical pharmacy
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| Research Institution | Aichi Gakuin University (2012)
Nigata University of Phermacy and Applied Life Sciences (2010-2011) |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
NAKAMURA Yutaka 新潟薬科大学, 応用生命科学部, 教授 (20267652)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 医療薬剤学 / 抗がん剤耐性 / 薬剤反応性 / 食品 / 癌 / トランスポータ / 薬学 |
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| Research Abstract |
Cancer drug resistance is mediated by anticancer drug effluxtransporter and cell survival transcription factor. In this study, I found dualinhibitors of drug efflux transporter and transcription factor from natural compounds. These natural compounds are useful for the development of a new anticancer drug for bettercancer chemotherapy.
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Report
(4 results)
Research Products
(20 results)
