| Project/Area Number |
22590171
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SHIRAISHI Yoshitake 金沢大学, 医学系, 技術専門員 (70467116)
OZAKI Noriyuki 金沢大学, 医学系, 教授 (40244371)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 内臓脂肪蓄積 / 肥満 / pancreatic polypeptide / 高脂肪食 / 摂食因子 / 脂肪幹細胞 / Suncus murinus / 褐色脂肪 / 内蔵脂肪蓄積 / 腸間膜脂肪蓄積 |
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| Research Abstract |
According to the result of the research of high-fat diet to Suncus murinus, it was showed the diets or nutrition could not result directly obesity or visceral fat accumulation, and the anti-visceral fat accumulation maybe relate to the fat metabolism in Suncus murinus. The receptor of pancreatic polypeptide, Y4, distributed wildly and expressed highly in the gastrointestinal tract, it implied the distribution was in connection with the phenomenon of obesity-resistance in Suncus murinus. Furthermore, compare to the adipose tissues in whole body, the distribution and the differentiation potency of adipose progenitor cells were lack in the mesenteric tissue of Suncus murinus.
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