Elucidation of the role of orexin type 2 receptor in the obesity resistance
| Project/Area Number |
22590228
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
|
|---|
| Research Institution | Toho University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Keywords | 解剖学 / 神経科学 / 体重制御 / 肥満 / 神経ペプチド / 摂食 / 神経解剖 / 神経回路 / 視床下部 / マウス / 体重調節 |
|---|
| Research Abstract |
To elucidate how orexin regulates body weight, we performed pharmacological and morphological studies. We found out that a specific subregion of the doral raphe nucleus is crucial for the regulation. In addition, we revealed the molecular diversity in the epigenetic mechanism of the neural groups including orexinergic neurons.
|
Report
(4 results)
Research Products
(23 results)
