| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Research Abstract |
The emotional stress enhanced the peripheral neuropathic pain induced by oxaliplatin, a chemotherapeutic agent, in this study. Therefore, psychological pressure may enhance the anticancer drugs-induced pain in cancer patients. We also found that both antidepressant amitriptyline and antipsychotic drug trifluoperazine alleviateanticancer drugs-induced pain by the attenuation of factors related to the onset of neuropathic pain in animal model.
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