An experimental and curative model of heartfailure with preserved ejection fraction in hypertension.
| Project/Area Number |
22590246
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General pharmacology
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| Research Institution | Saitama Medical University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
IIDA Shin-ichiro 埼玉医科大学, 医学部, 講師 (20513732)
YOSHIKAWA Ayumu 埼玉医科大学, 医学部, 助教 (00383224)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 心血管 / 血液 / 拡張期心不全 / 高血圧 / レニン・アンジオテンシン / 抗炎症 / COX2 / 循環器、高血圧 / 動物モデル / 炎症 / 消炎剤 |
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| Research Abstract |
Heart failure with preserved ejection fraction (HFpEF) occurs in 40% of the patients with heart failure and shows a poor outcome. However, treatment of HFpEF remains to be established. Hypertension is the most important factor in the progression to HFpEF. Therefore we sought to develop an experimental model of HFpEF from a model of hypertension.
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Report
(4 results)
Research Products
(7 results)
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[Presentation] アンジオテンシンII刺激による高血圧性拡張期心不全2009
Author(s)
Iida S, Aizaki Y, Yoshikawa A, Sun X, Matsumura M, Muramatsu T, Komiyama N, Nishimura S and Senbonmatsu T.
Organizer
第13回日本心血管内分泌代謝学会総会
Place of Presentation
大宮ソニックシティ(埼玉県)
Related Report
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