• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Analysis of microRNA expression in pancreatic carcinogenesis.

Research Project

Project/Area Number 22590318
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Human pathology
Research InstitutionJichi Medical University

Principal Investigator

FUKUSHIMA Noriyoshi  自治医科大学, 医学部, 教授 (40384937)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords膵管癌 / マイクロ RNA / 前癌病変 / 膵癌 / microRNA
Research Abstract

The aim of this study is to develop early diagnostic system of pancreatic cancer. The analyses of the early stage of pancreatic cancer, including pancreatic intraductal neoplasm have been performed. Total RNA from tissue specimens obtained by using microd

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (65 results)

All 2013 2012 2011 2010 Other

All Journal Article (29 results) (of which Peer Reviewed: 16 results) Presentation (23 results) (of which Invited: 2 results) Book (11 results) Remarks (2 results)

  • [Journal Article] IPMN 国際診療ガイドライン2012-残された課題-病理診断の判定基準-.2013

    • Author(s)
      福嶋敬宜
    • Journal Title

      日本膵臓学会誌「膵臓」

      Volume: 28巻2号 Pages: 156-161

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Multicenter study of serous cystic neoplasm of the Japan pancreas society2012

    • Author(s)
      Kimura W, Moriya T, Hanada K, Abe H, Yanagisawa A, Fukushima N
    • Journal Title

      Pancreas

      Volume: 41(3) Pages: 380-7

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of CT findings of biliary tract changes with autoimmune pancreatitis and extrahepatic bile duct cholangiocarcinoma2012

    • Author(s)
      Maeda E, Akahane M, Fukushima N
    • Journal Title

      Jpn J Radiol.

      Volume: 30(3) Pages: 227-34

    • NAID

      210000163116

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression2012

    • Author(s)
      Mohri D, Asaoka Y, Ijichi H, Ohta M, Tada M, Tanaka Y, Ikenoue T, Tateishi K, Isayama H, Kanai F, Fukushima N
    • Journal Title

      J Gastroenterol

      Volume: 47(2) Pages: 203-13

    • NAID

      10030296319

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 膵管内腫瘍の亜分類2012

    • Author(s)
      福嶋敬宜
    • Journal Title

      日消誌

      Volume: 109巻2号 Pages: 173-7

    • NAID

      10030310291

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Multicenter study of serous cystic neoplasm of the Japan pancreas society.2012

    • Author(s)
      Kimura W,et al.
    • Journal Title

      Pancreas

      Volume: 41 Issue: 3 Pages: 380-387

    • DOI

      10.1097/mpa.0b013e31822a27db

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Flow Cytometric Analysis of Kappa and Lambda Light Chain Expression in Endoscopic Biopsy Specimens before the Diagnosis of B-Cell Lymphoma2012

    • Author(s)
      Oka S, et al.
    • Journal Title

      Journal of Clinical and Experimental Hematopathology

      Volume: 52 Issue: 2 Pages: 127-131

    • DOI

      10.3960/jslrt.52.127

    • NAID

      10031120437

    • ISSN
      1346-4280, 1880-9952
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 膵漿液性嚢胞腫瘍(Serous cystic neoplasm)の全国症例調査―日本膵臓学会膵嚢胞性腫瘍委員会―2012

    • Author(s)
      木村理,ほか
    • Journal Title

      膵臓

      Volume: 27 Pages: 572-583

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IPMNの組織亜型(サブタイプ)分類の臨床病理学的意義.2012

    • Author(s)
      福嶋敬宜
    • Journal Title

      外科

      Volume: 75 Pages: 122-128

    • Related Report
      2012 Annual Research Report
  • [Journal Article] IPMNについての日本と欧米での考え方・取扱いの違い-病理の立場から.2012

    • Author(s)
      福嶋敬宜
    • Journal Title

      胆と膵

      Volume: 33 Pages: 1137-1140

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 膵管内腫瘍の亜分類.2012

    • Author(s)
      福嶋敬宜
    • Journal Title

      日本消化器病学会誌

      Volume: 109 Pages: 173-177

    • NAID

      10030310291

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Comparison of CT findings of biliary tract changes with autoimmune pancreatitis and extrahepatic bile duct cholangiocarcinoma2012

    • Author(s)
      Maeda E, et al
    • Journal Title

      Jpn J Radiol

      Volume: 30 Issue: 3 Pages: 227-34

    • DOI

      10.1007/s11604-011-0035-6

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Claudin-18 is an Early-Stage Marker of Pancreatic Carcinogenesis2011

    • Author(s)
      Tanaka M, Shibahara J, Fukushima N
    • Journal Title

      J Histochem Cytochem

      Volume: 59(10) Pages: 942-952

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinicopathological Features and Prognosis of Mucinous Cystic Neoplasm With Ovarian-Type Stroma A Multi-Institutional Study of the Japan Pancreas Society.2011

    • Author(s)
      Yamao K, Yanagisawa A, Takahashi K, Kimura W, Doi R, Fukushima N
    • Journal Title

      Pancreas

      Volume: 40 Pages: 67-71

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 胆膵腫瘍組織分類における癌取扱い規約と WHO 分類の異同と課題2011

    • Author(s)
      福嶋敬宜
    • Journal Title

      胆と膵

      Volume: 32

    • Related Report
      2012 Final Research Report
  • [Journal Article] Mucinous Cystic Neoplasm 悪性例の病理像および悪性頻度2011

    • Author(s)
      福嶋敬宜
    • Journal Title

      肝胆膵

    • Related Report
      2012 Final Research Report
  • [Journal Article] 膵,WHO 新分類の Overview2011

    • Author(s)
      福嶋敬宜
    • Journal Title

      肝胆膵

      Volume: 62

    • Related Report
      2012 Final Research Report
  • [Journal Article] Claudin-18 is an early-stage marker of pancreatic carcinogenesis2011

    • Author(s)
      Tanaka M, Shibahara J, Fukushima N, Shinozaki A, Umeda M, Ishikawa S, Kokudo N, Fukayama M
    • Journal Title

      J Histochem Cytochem

      Volume: 59 Issue: 10 Pages: 942-952

    • DOI

      10.1369/0022155411420569

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression2011

    • Author(s)
      Mohri D, et al
    • Journal Title

      J Gastroenterol

      Volume: 47 Issue: 2 Pages: 203

    • DOI

      10.1007/s00535-011-0482-y

    • NAID

      10030296319

    • URL

      https://pure.teikyo.jp/en/publications/a7334a9a-92cb-4868-b72a-28dc21dd553f

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 胆膵腫瘍組織分類における癌取扱い規約とWHO分類の異同と課題.:20112011

    • Author(s)
      福嶋敬宜
    • Journal Title

      胆と膵

      Volume: 32 Pages: 1271-1278

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 2010年WHO新分類のOverview2011

    • Author(s)
      福嶋敬宜
    • Journal Title

      肝胆膵

      Volume: 62 Pages: 39-43

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Undifferentiated Carcinoma of the Pancreas With/Without Osteoclast-like Giant Cells2010

    • Author(s)
      Tanaka M, Fukayama M, Fukushima N
    • Journal Title

      Pathol Case Reviews

      Volume: 15(6) Pages: 210-214

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 膵の SCN と MCN の病理2010

    • Author(s)
      福嶋敬宜
    • Journal Title

      肝胆膵画像

      Volume: 12 Pages: 687-692

    • Related Report
      2012 Final Research Report
  • [Journal Article] 胆膵疾患における細胞診・生検診断の病理学的問題点2010

    • Author(s)
      福嶋敬宜
    • Journal Title

      胆と膵

      Volume: 31 Pages: 815-818

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Journal Article] Intraepithelial neoplasia2010

    • Author(s)
      福嶋敬宜
    • Journal Title

      病理と臨床

      Volume: 28巻 Pages: 174-175

    • Related Report
      2012 Final Research Report
  • [Journal Article] 膵癌の前癌病変の病理2010

    • Author(s)
      福嶋敬宜
    • Journal Title

      肝胆膵画像

      Volume: 12 Pages: 161-166

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Journal Article] Clinicopathological Features and Prognosis of Mucinous Cystic Neoplasm With Ovarian-Type Stroma : A Multi-Institutional Study of the Japan Pancreas Society.2010

    • Author(s)
      Yamao K, et al.
    • Journal Title

      Pancreas

      Volume: 40 Pages: 67-71

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Undifferentiated Carcinoma of the Pancreas With/Without Osteoclast-like Giant Cells.2010

    • Author(s)
      Tanaka M, et al.
    • Journal Title

      Pathol Case Reviews

      Volume: 15 Pages: 210-214

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intraepithelial neoplasia2010

    • Author(s)
      福嶋敬宜
    • Journal Title

      病理と臨床(臨時増刊号)

      Volume: 28 Pages: 174-175

    • Related Report
      2010 Annual Research Report
  • [Presentation] 早期膵癌・前駆病変研究における多分野連携の重要性と病理医の役割 -国際 CAPS サミットからの考察2013

    • Author(s)
      福嶋敬宜
    • Organizer
      第102回 日本病理学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2013-06-06
    • Related Report
      2012 Final Research Report
  • [Presentation] International Consensus Study on the Terminology and Diagnosis of Tumoral Intraepithelial Neoplasms ("Adenomas" and "Intracystic Papillary Neoplasms" of WHO-2010) of the Gallbladder.2013

    • Author(s)
      Adsay V, et al.
    • Organizer
      The 102nd The Annual Meeting of United State and Canadian Academy of Pathology
    • Place of Presentation
      Baltimore, MD
    • Related Report
      2012 Final Research Report
  • [Presentation] International Consensus Study on the Terminology and Diagnosis of Tumoral Intraepithelial Neoplasms (“Adenomas” and “Intracystic Papillary Neoplasms” of WHO-2010) of the Gallbladder2013

    • Author(s)
      Adsay V, et al.
    • Organizer
      The 102nd The Annual Meeting of United State and Canadian Academy of Pathology,
    • Place of Presentation
      米国メリーランド州ボルチモア
    • Related Report
      2012 Annual Research Report
  • [Presentation] 浸潤性膵癌とその前駆病変 -病理学的視点から-2012

    • Author(s)
      福嶋敬宜
    • Organizer
      第75回 東北膵胆道疾患検討会
    • Place of Presentation
      仙台
    • Year and Date
      2012-07-20
    • Related Report
      2012 Final Research Report
  • [Presentation] 膵腫瘍 WHO 分類 2010 の概要2012

    • Author(s)
      福嶋敬宜
    • Organizer
      第101回 日本病理学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-04-26
    • Related Report
      2012 Final Research Report
  • [Presentation] 小膵癌(ts1)の臨床病理学的検討2012

    • Author(s)
      今田浩生
    • Organizer
      第101回 日本病理学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-04-26
    • Related Report
      2012 Final Research Report
  • [Presentation] IPMN についての日本と欧米での考え方・取扱いの違い-病理の立場から2012

    • Author(s)
      福嶋敬宜
    • Organizer
      第98回日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-04-19
    • Related Report
      2012 Final Research Report
  • [Presentation] 膵腫瘍WHO分類2010の概要2012

    • Author(s)
      福嶋敬宜
    • Organizer
      第101回 日本病理学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] IPMNについての日本と欧米での考え方・取扱いの違い-病理の立場から.2012

    • Author(s)
      福嶋敬宜
    • Organizer
      第98回 日本消化器病学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 膵IPMN切除後残膵再発症例の画像および病理学的検討.2012

    • Author(s)
      笹沼英紀,ほか
    • Organizer
      第43回 日本膵臓学会
    • Place of Presentation
      山形
    • Related Report
      2012 Annual Research Report
  • [Presentation] 浸潤性膵癌とその前駆病変 -病理学的視点から-2012

    • Author(s)
      福嶋敬宜
    • Organizer
      第75回 東北膵胆道疾患検討会
    • Place of Presentation
      仙台
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 小膵癌(ts1)の臨床病理学的検討2012

    • Author(s)
      今田浩生、ほか
    • Organizer
      第101回 日本病理学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] 消化器神経内分泌腫瘍の病理診断 ~分類の変遷と新たな展開~2011

    • Author(s)
      福嶋敬宜
    • Organizer
      第38回日本神経内分泌学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 消化器神経内分泌腫瘍の病理診断:分類の変遷と新たな展開2011

    • Author(s)
      福嶋敬宜
    • Organizer
      第38回日本神経内分泌学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 早期"膵癌と前駆病変- 病理学的視点から-2011

    • Author(s)
      福嶋敬宜
    • Organizer
      第12回北海道消化器画像・MIT 研究
    • Place of Presentation
      札幌
    • Year and Date
      2011-06-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 膵・胆管粘液産生腫瘍の病理2011

    • Author(s)
      福嶋敬宜
    • Organizer
      第9回病理・細胞診セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2011-01-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 胆膵腫瘍の病理診断-新 WHO 分類での改訂点もふまえて-2010

    • Author(s)
      福嶋敬宜
    • Organizer
      第22回北陸病理集談会
    • Place of Presentation
      福井
    • Year and Date
      2010-10-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 胆膵腫瘍の病理診断-新WHO分類での改訂点もふまえて2010

    • Author(s)
      福嶋敬宜
    • Organizer
      第22回北陸病理集談会
    • Place of Presentation
      福井
    • Year and Date
      2010-10-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] 病理組織形態学を基盤にした膵癌の前駆病変・癌間質へのアプローチ2010

    • Author(s)
      福嶋敬宜
    • Organizer
      自治医大シンポジウム
    • Place of Presentation
      栃木
    • Year and Date
      2010-09-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 胆膵病変の病理-新 WHO 分類(2010)での変更点もふまえて2010

    • Author(s)
      福嶋敬宜
    • Organizer
      第31回備後肝胆膵研究会
    • Place of Presentation
      福山
    • Year and Date
      2010-06-24
    • Related Report
      2012 Final Research Report
  • [Presentation] 胆膵病変の病理-新WHO分類(2010)での変更点もふまえて2010

    • Author(s)
      福嶋敬宜
    • Organizer
      第31回備後肝胆膵研究会
    • Place of Presentation
      広島
    • Year and Date
      2010-06-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 膵腫瘍WHO分類(第4版)の概要と改訂のポイント2010

    • Author(s)
      福嶋敬宜
    • Organizer
      第99回 日本病理学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 膵腫瘍 WHO 分類(第4 版)の概要と改訂のポイント.2010

    • Author(s)
      福嶋敬宜
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Book] 腫瘍性膵疾患2013

    • Author(s)
      福嶋敬宜
    • Publisher
      文光堂
    • Related Report
      2012 Final Research Report
  • [Book] 病理学・病理検査学2012

    • Author(s)
      福嶋敬宜
    • Total Pages
      296
    • Publisher
      医学書院
    • Related Report
      2012 Annual Research Report
  • [Book] 臨床に活かす病理診断学-消化管・肝胆膵編2011

    • Author(s)
      福嶋敬宜
    • Publisher
      医学書院
    • Related Report
      2012 Final Research Report
  • [Book] 臨床に活かす病理診断学-消化管・肝胆膵編2011

    • Author(s)
      福嶋敬宜, ほか
    • Total Pages
      300
    • Publisher
      医学書院
    • Related Report
      2011 Annual Research Report
  • [Book] Secondary tumours of the pancreas2010

    • Author(s)
      Iacobuzio-Donahue C,Fukushima N
    • Total Pages
      333
    • Publisher
      IARC Press
    • Related Report
      2012 Final Research Report
  • [Book] Diagnostic algorithms for tumours of the pancreas2010

    • Author(s)
      Klimstra DS, Fukushima N, Hruban RH, Kloppel G.
    • Publisher
      IARC Press
    • Related Report
      2012 Final Research Report
  • [Book] Ductal adenocarcinoma variants and mixed neoplasms of the pancreas.2010

    • Author(s)
      Fukushima N, Hruban RH, Kato Y, et al.
    • Publisher
      IARC Press
    • Related Report
      2012 Final Research Report
  • [Book] Serous cystic neoplasms of the pancreas2010

    • Author(s)
      Benoit Terris B, Fukushima N, Hruban RH
    • Publisher
      IARC Press
    • Related Report
      2012 Final Research Report
  • [Book] Mucinous cystic neoplasms of the pancreas2010

    • Author(s)
      Zamboni G, Fukushima N, Hruban RH, Kloppel G
    • Publisher
      IARC Press
    • Related Report
      2012 Final Research Report
  • [Book] Intraductal neoplasms of the pancreas2010

    • Author(s)
      Adsay NV, Fukushima N (他 8 名, 2 番目)
    • Publisher
      IARC Press
    • Related Report
      2012 Final Research Report
  • [Book] WHO Classification of Tumours of the Digestive System, 4th edition (Eds : Bosman, Hruban, Carneiro, Theise)2010

    • Author(s)
      Fukushima N, et al.
    • Total Pages
      27
    • Publisher
      IARC Press
    • Related Report
      2010 Annual Research Report
  • [Remarks] 自治医科大学 研究シーズ集

    • URL

      http://rseeds.jichi.ac.jp/research_seeds/public/ResearchResultDetail.php?publicId=h3en6ei9f4r65638ve57ji19vatbg3&resultCd=1&sectionCd=96

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://rseeds.jichi.ac.jp/research_seeds/public/SyozokuListTop.php

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi