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Mechanisms on the occurrence of myocardial infarctionfrom myocardial bridge

Research Project

Project/Area Number 22590322
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Human pathology
Research InstitutionToho University

Principal Investigator

ISHII Toshiharu  東邦大学, 医学部, 教授 (30101893)

Co-Investigator(Kenkyū-buntansha) AKASAKA Yoshikiyo  東邦大学, 医学部, 教授 (60202511)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords心筋架橋 / 冠状動脈 / 動脈硬化 / 心筋梗塞 / 心臓 / アテローム硬化 / 組織計測 / 動脈収縮関連蛋白 / 血行力学 / 病理解剖学
Research Abstract

Myocardial bridge(MB) existing in the coronary artery not only remarkably suppresses the atherosclerosis development in the coronary segment covered by MB, but also is influential to the atherosclerosis evolution and localization in the coronary artery segment proximal to the entrance of MB. When the mass volume of myocardium composing MB is large, such large MB induces the occurrence of MB. The patient age of such condition is significantly 8 years younger than that attacked by myocardial infarction without MB.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (14 results)

All 2013 2012 2011 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (5 results) (of which Invited: 1 results) Book (1 results)

  • [Journal Article] 心筋梗塞発生における心筋架橋の解剖学的特性2013

    • Author(s)
      石井壽晴
    • Journal Title

      脈管学

      Volume: 53 Pages: 59-65

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Association of variance in anatomical elements of myocardial bridge with coronary atherosclerosis.2013

    • Author(s)
      Iuchi A, Akasaka Y, Ishii Tet al.
    • Journal Title

      Atherosclerosis

      Volume: 227 Pages: 153-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histopathologic profiles of coronary atherosclerosis by myocardial bridge underlying myocardial infarction.2012

    • Author(s)
      Ishikawa Y, Akasaka Y, Ishii Tet al.
    • Journal Title

      Atherosclerosis

      Volume: 226 Pages: 118-23

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Myocardial bridge on coronary CTA: an innocent bystander or a culprit in myocardial infarction ?2012

    • Author(s)
      Nakanishi R, Ishii T et al.
    • Journal Title

      J Cardiovasc Comput Tomogr

      Volume: 6 Pages: 3-13

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Significance of the anatomical properties of a myocardial bridge in coronary heart disease.2011

    • Author(s)
      Ishikawa Y, Ishii Tet al.
    • Journal Title

      Circulation J

      Volume: 75 Pages: 1559-1566

    • NAID

      10029126127

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Anatomical characteristics of myocardial bridge in patients with myocardial infarction by multi-detector computed tomography.2011

    • Author(s)
      Takamura K, Ishii Tet al.
    • Journal Title

      Circulation J

      Volume: 75 Pages: 642-8

    • NAID

      10028102147

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Significance of the Anatomical Properties of a Myocardial Bridge in Coronary Heart Disease2011

    • Author(s)
      Ishikawa Y, Kawawa Y, Kohda E, Shimada K, Ishii T
    • Journal Title

      Circulation Journal

      Volume: 75 Issue: 7 Pages: 1559-1566

    • DOI

      10.1253/circj.CJ-10-1278

    • NAID

      10029126127

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Anatomical characteristics of myocardial bridge in patients with myocardial infarction by multi-detector computed tomography2011

    • Author(s)
      Takamura K, Ishii T, Yamazaki J
    • Journal Title

      Circulation J

      Volume: 75 Pages: 642-648

    • NAID

      10028102147

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 特別講演:心筋梗塞発生における心筋架橋の解剖学的特性2012

    • Author(s)
      石井壽晴
    • Organizer
      第53回日本脈管学会総会
    • Place of Presentation
      東京ステーションコンファレンス(東京都)
    • Year and Date
      2012-10-21
    • Related Report
      2012 Final Research Report
  • [Presentation] 左冠状動脈前下行枝の内膜病変に与える心筋架橋被覆部の解剖学的環境の影響2012

    • Author(s)
      井内亜美、赤坂喜清、石井壽晴ら
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      東京、京王プラザホテル(東京都)
    • Year and Date
      2012-04-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 創傷治癒期の線維芽細胞アポトーシスによる創傷修復の実行メカニズム2012

    • Author(s)
      赤坂喜清、石井壽晴ら
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2012-04-26
    • Related Report
      2012 Final Research Report
  • [Presentation] 心筋架橋を基盤とした心筋梗塞の発生機構2011

    • Author(s)
      石井寿晴
    • Organizer
      第52回日本脈管学会、脈管専門医教育セッション
    • Place of Presentation
      長良川国際会議場(岐阜県)(招待講演)
    • Year and Date
      2011-10-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 梗塞心における心筋架橋の解剖学的特性

    • Author(s)
      石井寿晴
    • Organizer
      第53回日本脈管学会総会
    • Place of Presentation
      東京ステーションコンファレンス(東京都)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Book] 心臓腫瘍(天野純編集、分担)2011

    • Author(s)
      石井寿晴
    • Publisher
      南江堂(東京)
    • Related Report
      2011 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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