Study to explore drug seeds for cryptosporidiosis
Project/Area Number |
22590378
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Parasitology (including Sanitary zoology)
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Research Institution | Kanazawa University |
Principal Investigator |
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Project Period (FY) |
2010 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | クリプトスポリジウム / アデノシン代謝 / 創薬 / 抗がん剤 / 核酸代謝 / 卵黄抗体 / 含硫アミノ酸代謝 / 腸管寄生原虫 |
Research Abstract |
Due to the lack of effective chemotherapy, severe cryptosporidiosis especially seen in immune-compromised host is often fetal. To explore drug seeds for the opportunistic infection, a screening method of the drug effect against Cryptosporidiumparvum in a cell culture model was successfully developed. Using the assessment procedure, anti-cryptosporidal efficacy was confirmed in a part of adenosine analogues, including anti-cancer drugs used in clinical sites.
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Report
(4 results)
Research Products
(19 results)
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[Presentation] 症例にみる寄生虫感染症2012
Author(s)
所 正治
Organizer
第19回中部圏支部微生物検査研究班宿泊研修会.
Place of Presentation
加賀片山津温泉佳水郷(石川県)
Year and Date
2012-11-10
Related Report
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